(Q14914363)

Zinc finger, RING/FYVE/PHD-type

1 reference

TNF receptor-associated factor 2

1 reference

MATH/TRAF domain, protein family

1 reference

TNF receptor-associated factor 2, MATH domain, protein family

1 reference

Zinc finger, RING-type, protein family

1 reference

Zinc finger, C3HC4 RING-type, protein family

1 reference

TNF receptor-associated factor, BIRC3 binding domain, protein family

1 reference

Zinc finger, TRAF-type, protein family

1 reference

Zinc finger, RING-type, conserved site, protein family

1 reference

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex

1 reference

25 May 2022

1 reference

25 May 2022

CD40 receptor binding

1 reference

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

ubiquitin-protein transferase activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

16 references

9 May 2019

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Suppressive effect of reactive oxygen species on CD40-induced B cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Bioinformatics and cellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

tumor necrosis factor receptor binding

IPI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

signaling receptor binding

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

tumor necrosis factor receptor binding

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein-containing complex binding

protein kinase binding

3 references

1 reference

14 February 2019

AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

1 reference

9 May 2019

The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex

CD40 receptor complex

1 reference

9 May 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

cytoplasmic side of plasma membrane

1 reference

9 May 2019

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

IRE1-TRAF2-ASK1 complex

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Nonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein-containing complex

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

IRE1-TRAF2-ASK1 complex

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

regulation of apoptotic process

biological process

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

positive regulation of tumor necrosis factor-mediated signaling pathway

1 reference

9 May 2019

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

positive regulation of JUN kinase activity

protein K63-linked ubiquitination

negative regulation of apoptotic process

1 reference

9 May 2019

The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

tumor necrosis factor-mediated signaling pathway

NAS

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

positive regulation of I-kappaB phosphorylation

1 reference

9 May 2019

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein catabolic process

1 reference

9 May 2019

Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

positive regulation of NF-kappaB transcription factor activity

IMP

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

TRAF family proteins link PKR with NF-kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

10 September 2018

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein ubiquitination

1 reference

9 May 2019

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

9 May 2019

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

cellular response to nitric oxide

1 reference

9 May 2019

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

programmed necrotic cell death

IMP

1 reference

9 May 2019

Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein autoubiquitination

IMP

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

protein-containing complex assembly

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429

tumor necrosis factor-mediated signaling pathway

ISO

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

positive regulation of NF-kappaB transcription factor activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

TRAF family proteins link PKR with NF-kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429

has part(s)

Zinc finger, TRAF-type

1 reference

Zinc finger, RING-type, conserved site

1 reference

Zinc finger, RING-type

1 reference

Zinc finger, C3HC4 RING-type

1 reference

TNF receptor-associated factor, BIRC3 binding domain

1 reference

MATH/TRAF domain

1 reference

TNF receptor-associated factor 2, MATH domain

1 reference