(Q15323346)

Zinc finger, NHR/GATA-type

1 reference

nuclear receptor

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

5 June 2018

The nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

transcription corepressor activity

1 reference

8 April 2019

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

RNA polymerase II cis-regulatory region sequence-specific DNA binding

1 reference

24 April 2018

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

DNA-binding transcription repressor activity, RNA polymerase II-specific

2 references

5 June 2018

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

8 April 2019

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

nuclear receptor activity

1 reference

8 April 2019

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

11 references

8 April 2019

Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erb alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Machine learning helps identify CHRONO as a circadian clock component

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Apolipoprotein A-IV reduces hepatic gluconeogenesis through nuclear receptor NR1D1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Structure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

transcription corepressor binding

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

RNA polymerase II cis-regulatory region sequence-specific DNA binding

ISA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

transcription cis-regulatory region binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

RNA polymerase II transcription regulatory region sequence-specific DNA binding

DNA-binding transcription factor activity, RNA polymerase II-specific

4 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

DNA-binding transcription repressor activity, RNA polymerase II-specific

transcription factor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

nuclear receptor coactivator activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

signaling receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

5 references

5 June 2018

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

6 references

8 April 2019

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

RNA polymerase II transcription regulator complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

negative regulation of transcription by RNA polymerase II

3 references

5 June 2018

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

5 June 2018

The nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20393&geneProductId=UniProtKB:P20393

transcription initiation from RNA polymerase II promoter

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

negative regulation of transcription, DNA-templated

TAS

6 references

8 April 2019

Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

The orphan nuclear receptor Rev-erbalpha recruits the N-CoR/histone deacetylase 3 corepressor to regulate the circadian Bmal1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

cellular response to lipopolysaccharide

1 reference

8 April 2019

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

negative regulation of toll-like receptor 4 signaling pathway

1 reference

8 April 2019

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

steroid hormone mediated signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

intracellular receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

negative regulation of transcription by RNA polymerase II

4 references

8 April 2019

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

The nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

multicellular organism development

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

hormone-mediated signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

regulation of circadian rhythm

3 references

3 references

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20393

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8901

IUPHAR/BPS Guide to PHARMACOLOGY

17 August 2016

1 reference

Guide to Pharmacology Ligand ID

8900

Nuclear receptor subfamily 1, group D, member 1

English

retrieved

17 August 2016

Gene Atlas image

PBB GE NR1D1 31637 s at fs.png
732 × 530; 12 KB

0 references

ortholog

found in taxon

house mouse

0 references

has part(s)

nuclear hormone receptor-type zinc finger

1 reference

Nuclear hormone receptor, ligand-binding domain

1 reference

Identifiers

0 references

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference