(Q18030926)

English

PTPN2

protein-coding gene in the species Homo sapiens

PTN2
PTPT
TC-PTP
TCELLPTP
TCPTP
protein tyrosine phosphatase, non-receptor type 2
protein tyrosine phosphatase non-receptor type 2

In more languages

Statements

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

protein-coding gene

1 reference

Ensembl Release 87

Ensembl gene ID

ENSG00000175354

Protein PTPN2 PDB 1l8k.png
1,093 × 766; 450 KB

0 references

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

Protein tyrosine phosphatase non-receptor type 2

1 reference

6 July 2017

UniProt protein ID

Tyrosine-protein phosphatase non-receptor type 2

1 reference

UniProt protein ID

20 March 2016

language of work or name

genetic association

rheumatoid arthritis

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_7148&ncbiId=5771

http://www.genome.gov/gwastudies/index.cfm?gene=PTPN2

Genetics of rheumatoid arthritis contributes to biology and drug discovery

25 May 2020

esophagus squamous cell carcinoma

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_3748&ncbiId=5771

http://www.genome.gov/gwastudies/index.cfm?gene=PTPN2

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

25 May 2020

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_10608&ncbiId=5771

http://www.genome.gov/gwastudies/index.cfm?gene=PTPN2

Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci

25 May 2020

Crohn's disease

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_8778&ncbiId=5771

http://www.genome.gov/gwastudies/index.cfm?gene=PTPN2

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

25 May 2020

type-1 diabetes

determination method

genome-wide association study

1 reference

https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_9744&ncbiId=5771

http://www.genome.gov/gwastudies/index.cfm?gene=PTPN2

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

25 May 2020

human chromosome 18

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

strand orientation

genomic assembly

genome assembly GRCh38

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

12785478

human chromosome 18

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

12785477

human chromosome 18

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

12929643

human chromosome 18

genomic assembly

genome assembly GRCh38

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

12929642

human chromosome 18

genomic assembly

Genome assembly GRCh37

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

cytogenetic location

18p11.21

1 reference

15 May 2022

7497

1 reference

15 May 2022

2 references

HomoloGene build68

7497

Orthologous MAtrix

https://omabrowser.org/oma/vps/P17706/

2 references

HomoloGene build68

7497

Orthologous MAtrix

https://omabrowser.org/oma/vps/P17706/

1 reference

HomoloGene build68

7497

Drosophila melanogaster

1 reference

HomoloGene build68

7497

1

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

2

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

3

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

4

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

5

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

body of pancreas

6

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

7

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

cerebellar hemisphere

8

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

minor salivary glands

9

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

bone marrow cells

10

1 reference

28 April 2022

https://bgee.org/bgee15_0/gene/ENSG00000175354

http://identifiers.org/ncbigene/5771

1 reference

Identifiers.org

http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069

Identifiers

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

10 April 2022

1 reference

15 May 2022

Ensembl gene ID

ENSG00000175354

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

Ensembl transcript ID

ENST00000592776

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000309660

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000327283

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000353319

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000585666

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000587497

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000587703

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000589086

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000589216

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000589444

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000591115

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000591305

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000591497

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000591901

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000592059

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000645816

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000645191

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000646492

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000643397

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000643900

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

ENST00000644814

1 reference

ensembl Release 106

Ensembl gene ID

ENSG00000175354

0 references

HGNC gene symbol

1 reference

15 May 2022

1 reference

15 May 2022

1 reference

Online Mendelian Inheritance in Man

19 August 2019

1 reference

based on heuristic

inferred by common HGNC mappings on source and on Wikidata

15 June 2023

Sitelinks

Wikipedia(2 entries)

enwiki PTPN2
ukwiki PTPN2

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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