(Q21096399)

High mobility group box domain superfamily

1 reference

High mobility group box domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

HSR domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SAND domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transcription corepressor activity

protein domain specific binding

1 reference

8 April 2019

Chromatin components as part of a putative transcriptional repressing complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

chromo shadow domain binding

1 reference

8 April 2019

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

protein homodimerization activity

1 reference

26 September 2017

Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

1 reference

8 April 2019

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

transcription coactivator activity

2 references

transcription factor binding

1 reference

26 September 2017

Sp100 interacts with ETS-1 and stimulates its transcriptional activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

10 references

8 April 2019

Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Chromatin components as part of a putative transcriptional repressing complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Human cytomegalovirus infection causes degradation of Sp100 proteins that suppress viral gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

DNA-binding transcription factor activity, RNA polymerase II-specific

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

protein dimerization activity

1 reference

8 April 2019

Interaction of SP100 with HP1 proteins: a link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Dynamic regulation of p53 subnuclear localization and senescence by MORC3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Dynamic regulation of p53 subnuclear localization and senescence by MORC3

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Cellular localization, expression, and structure of the nuclear dot protein 52

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

1 reference

8 April 2019

Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

1 reference

26 September 2017

Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of DNA-binding transcription factor activity

biological process

1 reference

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

negative regulation of endothelial cell migration

1 reference

8 April 2019

SP100 inhibits ETS1 activity in primary endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of viral transcription

1 reference

26 September 2017

Differential role of Sp100 isoforms in interferon-mediated repression of herpes simplex virus type 1 immediate-early protein expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

regulation of angiogenesis

1 reference

8 April 2019

SP100 inhibits ETS1 activity in primary endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

1 reference

8 April 2019

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of DNA binding

1 reference

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of protein export from nucleus

1 reference

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Suppression of alternative lengthening of telomeres by Sp100-mediated sequestration of the MRE11/RAD50/NBS1 complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

response to type I interferon

3 references

8 April 2019

The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

SP100 expression modulates ETS1 transcriptional activity and inhibits cell invasion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

8 April 2019

Cellular localization, expression, and structure of the nuclear dot protein 52

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

regulation of Fas signaling pathway

1 reference

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

retinoic acid receptor signaling pathway

1 reference

26 September 2017

Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

response to retinoic acid

IC

1 reference

26 September 2017

Common properties of nuclear body protein SP100 and TIF1alpha chromatin factor: role of SUMO modification

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

regulation of transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

response to interferon-gamma

type I interferon signaling pathway

1 reference

8 April 2019

The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

regulation of extrinsic apoptotic signaling pathway via death domain receptors

IC

1 reference

8 April 2019

FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

negative regulation of transcription, DNA-templated

negative regulation of nucleic acid-templated transcription

1 reference

26 September 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23497&geneProductId=UniProtKB:P23497

maintenance of protein location

1 reference

8 April 2019

Recruitment of NBS1 into PML oncogenic domains via interaction with SP100 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

Sp100 is important for the stimulatory effect of homeodomain-interacting protein kinase-2 on p53-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23497

High mobility group box domain

has part(s)

1 reference

SAND domain

1 reference

HSR domain

1 reference