(Q21108143)

http://www.ebi.ac.uk/interpro/protein/P24522

Growth arrest and DNA damage-inducible protein GADD45

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24522

Ribosomal protein L7Ae/L30e/S12e/Gadd45, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

9 references

8 April 2019

TAFII70 isoform-specific growth suppression correlates with its ability to complex with the GADD45a protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

protein homodimerization activity

IPI

1 reference

8 April 2019

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

protein heterodimerization activity

1 reference

8 April 2019

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

protein N-terminus binding

IPI

1 reference

8 April 2019

Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

RNA polymerase II core promoter sequence-specific DNA binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

16 July 2018

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

5 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

16 July 2018

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

8 April 2019

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

negative regulation of protein kinase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

signal transduction in response to DNA damage

1 reference

8 April 2019

Feedback between p21 and reactive oxygen production is necessary for cell senescence

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24522&geneProductId=UniProtKB:P24522

positive regulation of JNK cascade

1 reference

8 April 2019

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

cellular response to mechanical stimulus

1 reference

8 April 2019

Expression of the Bcl-2 protein BAD promotes prostate cancer growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

positive regulation of reactive oxygen species metabolic process

IEP

1 reference

8 April 2019

Feedback between p21 and reactive oxygen production is necessary for cell senescence

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

positive regulation of apoptotic process

IMP

1 reference

8 April 2019

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

cellular response to ionizing radiation

1 reference

8 April 2019

Feedback between p21 and reactive oxygen production is necessary for cell senescence

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

1 reference

8 April 2019

Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

positive regulation of p38MAPK cascade

TAS

1 reference

8 April 2019

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24522

Ribosomal protein L7Ae/L30e/S12e/Gadd45

TAS

regulation of cell cycle

1 reference

stated in

InterPro Release 71.0