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Neuregulin 2
mammalian protein found in Homo sapiens
pro-NRG2
neural- and thymus-derived activator for ErbB kinases
pro-neuregulin-2, membrane-bound isoform
NRG2
divergent of neuregulin-1
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O14511
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O14511
encoded by
NRG2
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O14511
molecular function
growth factor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O14511
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
signaling receptor binding
determination method
TAS
1 reference
retrieved
24 April 2018
stated in
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
TAS
protein tyrosine kinase activity
determination method
TAS
1 reference
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
TAS
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
determination method
TAS
1 reference
retrieved
7 November 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
TAS
signaling receptor binding
determination method
IBA
TAS
2 references
retrieved
10 September 2018
stated in
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
TAS
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
IBA
signaling receptor binding
determination method
IBA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IBA
cell component
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O14511
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O14511
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
plasma membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O14511
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
extracellular region
determination method
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O14511
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
intracellular anatomical structure
determination method
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
IEA
extracellular space
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IBA
biological process
MAPK cascade
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
signal transduction
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
retrieved
8 April 2019
stated in
Ligands for ErbB-family receptors encoded by a neuregulin-like gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
regulation of cell motility
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
phosphatidylinositol phosphate biosynthetic process
determination method
IEA
1 reference
retrieved
7 November 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
IEA
peptidyl-tyrosine phosphorylation
determination method
IEA
1 reference
retrieved
7 November 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
IEA
ERBB2 signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
intracellular signal transduction
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IBA
animal organ development
determination method
IBA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O14511&geneProductId=UniProtKB:O14511
determination method
IBA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
positive regulation of protein kinase B signaling
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
TAS
nervous system development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14511
determination method
IEA
Identifiers
RefSeq protein ID
NP_001171864
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
NP_004874
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
NP_053584
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
NP_053585
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
NP_053586
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_005268590
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_006714873
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_011536015
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_016865553
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_016865554
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
XP_024302029
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
9542
UniProt protein ID
O14511
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O14511
Ensembl protein ID
ENSP00000289409
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000289409
ENSP00000289422
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000289422
ENSP00000342660
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000342660
ENSP00000351323
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000351323
ENSP00000354910
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000354910
ENSP00000367483
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000367483
ENSP00000444235
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000444235
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