(Q21133153)

http://www.ebi.ac.uk/interpro/protein/Q92819

Hyaluronan synthase 2

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q92819

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

glycosyltransferase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

hyaluronan synthase activity

5 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

identical protein binding

IPI

1 reference

8 April 2019

Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

hyaluronan synthase activity

IPI

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

integral component of plasma membrane

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of keratinocyte proliferation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

hyaluronan biosynthetic process

6 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

16 July 2018

Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92819&geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of cell migration

1 reference

8 April 2019

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

cellular response to tumor necrosis factor

IMP

1 reference

8 April 2019

Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

cellular response to platelet-derived growth factor stimulus

1 reference

8 April 2019

Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

cellular response to fluid shear stress

IDA

1 reference

8 April 2019

Shear stress increases endothelial hyaluronan synthase 2 and hyaluronan synthesis especially in regard to an atheroprotective flow profile

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of smooth muscle cell migration

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of keratinocyte migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of substrate adhesion-dependent cell spreading

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of hyaluronan biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

extracellular matrix assembly

3 references

cellular response to interleukin-1

1 reference

8 April 2019

Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of cell population proliferation

IEP

1 reference

8 April 2019

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

extracellular polysaccharide biosynthetic process

IMP

3 references

hyaluronan metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

positive regulation of monocyte aggregation

1 reference

8 April 2019

Proinflammatory cytokines induce hyaluronan synthesis and monocyte adhesion in human endothelial cells through hyaluronan synthase 2 (HAS2) and the nuclear factor-kappaB (NF-kappaB) pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

regulation of extracellular matrix assembly

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

hyaluronan biosynthetic process

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92819