(Q21152127)

Growth factor receptor cysteine-rich domain superfamily

1 reference

Galactose-binding-like domain superfamily

1 reference

Peptidase S8/S53 domain superfamily

1 reference

Peptidase S8, pro-domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

Peptidase S8, pro-domain, protein family

1 reference

Growth factor receptor domain 4, protein family

1 reference

Kexin/furin catalytic domain, protein family

1 reference

PLAC, protein family

1 reference

Peptidase S8, subtilisin, Ser-active site, protein family

1 reference

P domain family

1 reference

EGF-like domain, protein family

1 reference

Peptidase S8, subtilisin, Asp-active site, protein family

1 reference

Subtilase

1 reference

Furin-like repeat, protein family

1 reference

Peptidase S8, subtilisin, His-active site, protein family

1 reference

Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

nerve growth factor binding

1 reference

8 April 2019

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

serine-type peptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

serine-type endopeptidase activity

IEA

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

8 April 2019

A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

serine-type endopeptidase activity

IPI

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases

IBA

endopeptidase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

1 reference

24 April 2018

Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

1 reference

10 September 2018

Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

endoplasmic reticulum

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

10 September 2018

Functional analysis of human PACE4-A and PACE4-C isoforms: identification of a new PACE4-CS isoform

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

collagen-containing extracellular matrix

TAS

1 reference

10 September 2018

Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

2 references

collagen-containing extracellular matrix

2 references

glycoprotein metabolic process

1 reference

8 April 2019

PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

8 April 2019

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

10 September 2018

Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

2 references

regulation of BMP signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

determination of left/right symmetry

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

peptide hormone processing

IEA

1 reference

10 September 2018

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29122&geneProductId=UniProtKB:P29122

zygotic determination of anterior/posterior axis, embryo

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

nerve growth factor production

IEA

1 reference

8 April 2019

Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

regulation of lipoprotein lipase activity

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

PACE4 is a member of the mammalian propeptidase family that has overlapping but not identical substrate specificity to PACE

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Processing of prothyrotropin-releasing hormone by the family of prohormone convertases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

nerve growth factor processing

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29122

1 reference

Peptidase S8, subtilisin, Asp-active site

1 reference

Peptidase S8, pro-domain

1 reference

P domain

1 reference

Growth factor receptor domain 4

1 reference

Furin-like repeat

1 reference

peptidase S8, subtilisin, His-active site

1 reference

Peptidase S8, subtilisin, Ser-active site

1 reference

EGF-like domain

1 reference

peptidase S8/S53 domain

1 reference

Kexin/furin catalytic domain

1 reference