(Q21497883)

small conductance calcium-activated potassium channel

1 reference

calmodulin-binding proteins

1 reference

based on heuristic

inferred from protein domain or family

Potassium channel domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

24 April 2018

Identification and characterization of a novel, shorter isoform of the small conductance Ca2+ -activated K+ channel SK2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

small conductance calcium-activated potassium channel activity

3 references

24 April 2018

Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

24 April 2018

Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

24 April 2018

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

1 reference

14 February 2019

Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

calcium-activated potassium channel activity

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

small conductance calcium-activated potassium channel activity

IEA

5 references

14 February 2019

Molecular properties of small-conductance Ca2+-activated K+ channels expressed in murine colonic smooth muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

1 reference

14 February 2019

Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

smooth endoplasmic reticulum

1 reference

14 February 2019

Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

3 references

14 February 2019

Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Functional interaction with filamin A and intracellular Ca2+ enhance the surface membrane expression of a small-conductance Ca2+-activated K+ (SK2) channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

1 reference

14 February 2019

Alpha-actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca2+-activated K+ channel (SK2 channel)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

integral component of membrane

3 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

1 reference

24 April 2018

Identification and characterization of a novel, shorter isoform of the small conductance Ca2+ -activated K+ channel SK2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

potassium ion transmembrane transport

1 reference

24 April 2018

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

membrane repolarization during atrial cardiac muscle cell action potential

IMP

1 reference

14 February 2019

Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

IMP

potassium ion transport

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P58390&geneProductId=UniProtKB:P58390

regulation of neuronal synaptic plasticity

ISO

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

IEA

potassium ion transport

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P58390

potassium ion transmembrane transport

IEA

Calmodulin-binding domain

1 reference

Potassium channel domain

1 reference