(Q24190)

English

Neurotrophin 3

mammalian protein found in Homo sapiens

nerve growth factor 2
NTF3
HDNF
NGF-2
neurotrophic factor
neurotrophin-3

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

Cystine-knot cytokine

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20783

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20783

Nerve growth factor-related, protein family

1 reference

based on heuristic

inferred from protein domain or family

Nerve growth factor conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

neurotrophin p75 receptor binding

determination method

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20783&geneProductId=UniProtKB:P20783

determination method

neurotrophin receptor binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

chemoattractant activity

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

growth factor activity

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

cytoplasmic vesicle

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

extracellular region

determination method

extracellular space

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

synaptic vesicle

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

biological process

regulation of apoptotic process

determination method

1 reference

8 April 2019

Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

negative regulation of neuron apoptotic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

regulation of neuron differentiation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

activation of protein kinase B activity

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

neuron projection morphogenesis

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

activation of GTPase activity

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of receptor internalization

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

transmembrane receptor protein tyrosine kinase signaling pathway

determination method

1 reference

21 June 2018

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20783&geneProductId=UniProtKB:P20783

determination method

positive regulation of cell migration

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

cell-cell signaling

determination method

1 reference

8 April 2019

Molecular cloning of a human gene that is a member of the nerve growth factor family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of peptidyl-serine phosphorylation

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

induction of positive chemotaxis

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

negative regulation of peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of cell population proliferation

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of actin cytoskeleton reorganization

determination method

1 reference

8 April 2019

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

signal transduction

determination method

1 reference

8 April 2019

Molecular cloning of a human gene that is a member of the nerve growth factor family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive chemotaxis

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

nervous system development

determination method

1 reference

8 April 2019

Neurotrophin 3 is a mitogen for cultured neural crest cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

regulation of signaling receptor activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of phospholipase C activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of phosphatidylinositol 3-kinase signaling

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

peripheral nervous system development

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

nerve development

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

nerve growth factor signaling pathway

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

modulation of chemical synaptic transmission

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

positive regulation of neurotrophin TRK receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20783

determination method

Gene Atlas image

PBB GE NTF3 206706 at fs.png
732 × 530; 12 KB

0 references

http://purl.uniprot.org/uniprot/P20783

1 reference

Identifiers.org

Nerve growth factor conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20783

Nerve growth factor-related

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20783

Identifiers

CAS Registry Number

0 references

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000328738

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000328738

ENSP00000397297

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000397297

1 reference

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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