(Q24302442)

English

Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites

scientific article

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scholarly article

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Dynamic changes in C-Raf phosphorylation and 14-3-3 protein binding in response to growth factor stimulation: differential roles of 14-3-3 protein binding sites (English)

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phosphorylation

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6

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Michael Sendtner

7

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author name string

Mirko Hekman

1

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Stefan Wiese

2

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Renate Metz

3

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Stefan Albert

4

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Jakob Troppmair

5

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Ulf R Rapp

8

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language of work or name

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publication date

2 April 2004

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Journal of Biological Chemistry

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279

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14

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14074-86

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Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

The ins and outs of Raf kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Isotype-specific functions of Raf kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Regulation of Raf through phosphorylation and N terminus-C terminus interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Characterization of murine A-raf, a new oncogene related to the v-raf oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Associations of B- and C-Raf with cholesterol, phosphatidylserine, and lipid second messengers: preferential binding of Raf to artificial lipid rafts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Regulation of Raf-1 activation and signalling by dephosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Inhibition by cAMP of Ras-dependent activation of Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Protein kinase C alpha activates RAF-1 by direct phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

The structural basis for 14-3-3:phosphopeptide binding specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Interaction of the protein kinase Raf-1 with 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Activation of Raf-1 by 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

raf family serine/threonine protein kinases in mitogen signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Dephosphorylation of Ser-259 regulates Raf-1 membrane association

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Isoform-specific localization of A-RAF in mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Lipid rafts and signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Ras signaling: PP2A puts Ksr and Raf in the right place

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

21 January 2018

Production and characterization of monoclonal antibodies against human BAD protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of Raf in vascular protection from distinct apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

7 January 2021

based on heuristic

inferred from DOI database lookup

Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309620200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M309620200

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