(Q24304488)

Telomeric repeat binding factor 2

1 reference

BLM RecQ like helicase

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protein C-terminus binding

1 reference

1 reference

6

Vilhelm A Bohr

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author name string

Patricia L Opresko

1

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Cayetano von Kobbe

2

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Jean-Philippe Laine

3

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Jeanine Harrigan

4

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Ian D Hickson

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

25 October 2002

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published in

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volume

277

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issue

43

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page(s)

41110-9

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cites work

Molecular genetics of Bloom's syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

DNA helicase deficiencies associated with cancer predisposition and premature ageing disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

The Werner syndrome protein is a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Cellular senescence, cancer and aging: the telomere connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Telomere states and cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Control of human telomere length by TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

TRF2 Protects Human Telomeres from End-to-End Fusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

DNA damage and repair in telomeres: relation to aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Nuclear structure in normal and Bloom syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Oligomeric ring structure of the Bloom's syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

A mammalian factor that binds telomeric TTAGGG repeats in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

p53 Modulates the exonuclease activity of Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Werner syndrome protein: biochemical properties and functional interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Nucleolar localization of the Werner syndrome protein in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

TRF1 binds a bipartite telomeric site with extreme spatial flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Interaction of human Ku70 with TRF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

Defending genome integrity during DNA replication: a proposed role for RecQ family helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

SGS1 is required for telomere elongation in the absence of telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021

Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205396200

7 January 2021