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ABL1 BCR::ABL
genetic variant
T(9;22)(Q34;Q11)
BCR-ABL
BCR-ABL1
BCR::ABL
In more languages
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Statements
instance of
transcript fusion
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
chromosome
human chromosome 9
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
human chromosome 22
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
genomic start
133729451
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
23522397
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
genomic end
133763063
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
23632600
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
biological variant of
ABL1
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
positive therapeutic predictor for
imatinib
medical condition treated
chronic myeloid leukemia
determination method
CIViC evidence level A
rating
CIViC 5-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/344
stated in
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review
imatinib
medical condition treated
acute myeloid leukemia
determination method
CIViC evidence level A
rating
CIViC 5-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/259
stated in
Novel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571.
dasatinib monohydrate
determination method
CIViC evidence level A
rating
CIViC 4-star trust rating
medical condition treated
chronic myeloid leukemia
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/261
stated in
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review
nilotinib
determination method
CIViC evidence level A
rating
CIViC 4-star trust rating
medical condition treated
chronic myeloid leukemia
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/261
stated in
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review
dasatinib monohydrate
determination method
CIViC evidence level C
rating
CIViC 3-star trust rating
medical condition treated
acute lymphocytic leukemia
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/4436
stated in
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
dasatinib monohydrate
determination method
CIViC evidence level C
rating
CIViC 4-star trust rating
medical condition treated
chronic myeloid leukemia
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/4706
stated in
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
negative therapeutic predictor for
imatinib
determination method
CIViC evidence level D
rating
CIViC 3-star trust rating
medical condition treated
acute myeloid leukemia
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/232
stated in
Novel targeted therapies for Bcr-Abl positive acute leukemias: beyond STI571.
positive diagnostic predictor for
chronic myeloid leukemia
determination method
CIViC evidence level C
rating
CIViC 2-star trust rating
statement disputed by
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/213
stated in
Molecular-defined clonal evolution in patients with chronic myeloid leukemia independent of the BCR-ABL status
chronic myeloid leukemia
determination method
CIViC evidence level A
rating
CIViC 4-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/220
stated in
BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: a review
Identifiers
CIViC variant ID
1
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
HGVS nomenclature
no value
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1
Sitelinks
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Wiktionary
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Multilingual sites
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