(Q27740172)

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A structural basis for mutational inactivation of the tumour suppressor Smad4

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A structural basis for mutational inactivation of the tumour suppressor Smad4 (English)

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author name string

Y Shi

1

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A Hata

2

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R S Lo

3

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J Massagué

4

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N P Pavletich

5

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language of work or name

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publication date

3 July 1997

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388

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6637

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87-93

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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TGFbeta signaling: receptors, transducers, and Mad proteins.

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Nomenclature: vertebrate mediators of TGFbeta family signals.

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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Intracellular signalling: the mad way to do it.

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

inferred from DOI database lookup

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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MADR1, a MAD-related protein that functions in BMP2 signaling pathways

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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A human Mad protein acting as a BMP-regulated transcriptional activator

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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The CCP4 suite: programs for protein crystallography

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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SQUASH - combining constraints for macromolecular phase refinement and extension

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Improved methods for building protein models in electron density maps and the location of errors in these models

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

1 reference

https://api.crossref.org/works/10.1038%2F40431

7 January 2021

based on heuristic

inferred from DOI database lookup

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