(Q28301955)

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

The SCF ubiquitin ligase: insights into a molecular machine

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Pocket proteins and cell cycle control

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Size control in animal development

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Gene-specific regulation by general translation factors

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

A synthetic inhibitor of the mitogen-activated protein kinase cascade

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Regulation of carbamoyl phosphate synthetase by MAP kinase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Essential role for ERK2 mitogen-activated protein kinase in placental development

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Upstream and downstream of mTOR

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Identification of the Anti-proliferative protein Tob as a MAPK substrate

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

c-MYC: more than just a matter of life and death

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

The retinoblastoma protein and cell cycle control

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

TOR signaling in growth and metabolism

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Extracellular signal-regulated kinase 2 is necessary for mesoderm differentiation

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targets

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1210414

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

Global analysis of protein phosphorylation in yeast

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

Placental development: lessons from mouse mutants

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

Mitogen-activated protein kinase kinase 2 activation is essential for progression through the G2/M checkpoint arrest in cells exposed to ionizing radiation.

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Transcriptional regulation and transformation by Myc proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Regulation of p21(cip1) expression by growth factors and the extracellular matrix reveals a role for transient ERK activity in G1 phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Dual role of MEK/ERK signaling in senescence and transformation of intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

E2F target genes: unraveling the biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Phosphorylation regulates nucleophosmin targeting to the centrosome during mitosis as detected by cross-reactive phosphorylation-specific MKK1/MKK2 antibodies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Tumour biology: senescence in premalignant tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Diverse Mitogenic Agents Induce the Phosphorylation of Two Related 42,000-Dalton Proteins on Tyrosine in Quiescent Chick Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The p42/p44 mitogen-activated protein kinase activation triggers p27Kip1 degradation independently of CDK2/cyclin E in NIH 3T3 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Colony-stimulating factor-1 receptor utilizes multiple signaling pathways to induce cyclin D2 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The duration, magnitude and compartmentalization of ERK MAP kinase activity: mechanisms for providing signaling specificity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Dual growth arrest pathways in astrocytes and astrocytic tumors in response to Raf-1 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The role of erk1 and erk2 in multiple stages of T cell development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Insulin and phorbol ester stimulate initiation factor eIF-4E phosphorylation by distinct pathways in Chinese hamster ovary cells overexpressing the insulin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p42-MAP kinase is activated in EGF-stimulated interphase but not in metaphase-arrested HeLa cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Control of the cell morphology and the S phase entry by mitogen-activated protein kinase kinase. A regulatory role of its n-terminal region.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

An analysis of Mek1 signaling in cell proliferation and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Hepatocyte growth factor induces redistribution of p21(CIP1) and p27(KIP1) through ERK-dependent p16(INK4a) up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The Rb/E2F pathway: expanding roles and emerging paradigms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mechanism of mitosis-specific activation of MEK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

MEK inhibition and phosphorylation of serine 4 on B23 are two coincident events in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Identification of CDK4 as a target of c-MYC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Transcriptional regulation by extracellular signals: mechanisms and specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Growth-factor-dependent mitogenesis requires two distinct phases of signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

How cells coordinate growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Alpha-thrombin-induced tyrosine phosphorylation of 43,000- and 41,000-Mr proteins is independent of cytoplasmic alkalinization in quiescent fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

New functional activities for the p21 family of CDK inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Regulation of exit from quiescence by p27 and cyclin D1-CDK4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Signal transduction through MAP kinase cascades

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The MAP kinase pathway is required for entry into mitosis and cell survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ras versus cyclin-dependent kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

To cycle or not to cycle: a critical decision in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

eIF4E--from translation to transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Rheb fills a GAP between TSC and TOR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ribosome biogenesis and cell growth: mTOR coordinates transcription by all three classes of nuclear RNA polymerases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cell cycle reentry of mammalian fibroblasts is accompanied by the sustained activation of p44mapk and p42mapk isoforms in the G1 phase and their inactivation at the G1/S transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Involvement of stress-activated protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Molecular interpretation of ERK signal duration by immediate early gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The anaphase-promoting complex: proteolysis in mitosis and beyond

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

MAP kinase cascade is required for p27 downregulation and S phase entry in fibroblasts and epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Distinct cell cycle timing requirements for extracellular signal-regulated kinase and phosphoinositide 3-kinase signaling pathways in somatic cell mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Requirement of MAP kinase for differentiation of fibroblasts to adipocytes, for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Targeting the mitogen-activated protein kinase cascade to treat cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Activation of the MKK/ERK pathway during somatic cell mitosis: direct interactions of active ERK with kinetochores and regulation of the mitotic 3F3/2 phosphoantigen.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The emerging roles of translation factor eIF4E in the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The mitogen-activated protein kinase kinase/extracellular signal-regulated kinase cascade activation is a key signalling pathway involved in the regulation of G(1) phase progression in proliferating hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Proliferation of cancer cells despite CDK2 inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Gamma interferon and cadmium treatments modulate eukaryotic initiation factor 4E-dependent mRNA transport of cyclin D1 in a PML-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Ro 09-2210 exhibits potent anti-proliferative effects on activated T cells by selectively blocking MKK activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Oncogenic signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Mice lacking a transcriptional corepressor Tob are predisposed to cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

The cyclin-dependent kinase inhibitor p21cip1 mediates the growth inhibitory effect of phorbol esters in human venous endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210414

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210414

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2206980

1043458445

0 references

2206980

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference