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Protection of mammalian telomeres
scientific article (publication date: 21 January 2002)
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Protection of mammalian telomeres
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21 January 2002
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Oncogene
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MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans
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Strand-Specific Postreplicative Processing of Mammalian Telomeres
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7 January 2021
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DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes
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Pot1, the putative telomere end-binding protein in fission yeast and humans
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Ku binds telomeric DNA in vitro
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Telomeric localization of TRF2, a novel human telobox protein
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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2
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Telomerase activity in normal and malignant hematopoietic cells
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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
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Regulation of telomere length and function by a Myb-domain protein in fission yeast
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DNA end-joining: from yeast to man
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Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.
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CELL BIOLOGY: Enhanced: Telomere Capping--One Strand Fits All
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A new connection at human telomeres: association of the Mre11 complex with TRF2.
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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
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Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere
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Telomere dynamics, end-to-end fusions and telomerase activation during the human fibroblast immortalization process
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Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2
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Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
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The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.
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Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
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Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.
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Yeast Ku as a regulator of chromosomal DNA end structure
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Mammalian telomeres end in a large duplex loop
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7 January 2021
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Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability
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7 January 2021
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Inhibition of telomerase limits the growth of human cancer cells.
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Crossref
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7 January 2021
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Ku is associated with the telomere in mammals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ku acts in a unique way at the mammalian telomere to prevent end joining
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2
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7 January 2021
based on heuristic
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A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
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7 January 2021
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Identification of human Rap1: implications for telomere evolution
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Crossref
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7 January 2021
based on heuristic
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The Saccharomyces CDC13 protein is a single-strand TG1-3 telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genes involved in senescence and immortalization
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7 January 2021
based on heuristic
inferred from DOI database lookup
A mutant with a defect in telomere elongation leads to senescence in yeast
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation
1 reference
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
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inferred from DOI database lookup
Cdc13 subcomplexes regulate multiple telomere functions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The terminal DNA structure of mammalian chromosomes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
t-loops at trypanosome telomeres.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomeres of polytene chromosomes in a ciliated protozoan terminate in duplex DNA loops
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere maintenance is dependent on activities required for end repair of double-strand breaks.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc13 delivers separate complexes to the telomere for end protection and replication
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of T antigen interactions with p53 in tumorigenesis
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Living with genome instability: plant responses to telomere dysfunction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular senescence: mitotic clock or culture shock?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RAP1: a protean regulator in yeast.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of human Ku70 with TRF2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human papillomavirus E6 and E7: proteins which deregulate the cell cycle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A DNA damage response pathway controlled by Tel1 and the Mre11 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRF2 Protects Human Telomeres from End-to-End Fusions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal human chromosomes have long G-rich telomeric overhangs at one end
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1205080
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7 January 2021
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Identifiers
DOI
10.1038/SJ.ONC.1205080
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11850778
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1903385
Dimensions Publication ID
1023271467
0 references
OpenCitations bibliographic resource ID
1903385
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1903385
PubMed ID
11850778
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=11850778
retrieved
30 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1903385
ResearchGate publication ID
11510234
0 references
Springer Nature article ID
10.1038/sj.onc.1205080
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