(Q30480194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

Melania E Mercado-Pimentel

24 December 2019

author

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

Raymond B Runyan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

author name string

Antony D Hubbard

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

language of work or name

English

0 references

publication date

23 December 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

304

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

page(s)

420-432

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development

24 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Characterization of murine S-endoglin isoform and its effects on tumor development.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Interaction and functional interplay between endoglin and ALK-1, two components of the endothelial transforming growth factor-beta receptor complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Frzb modulates Wnt-9a-mediated beta-catenin signaling during avian atrioventricular cardiac cushion development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Coronary vessel development: the epicardium delivers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Transforming growth factor beta in cardiovascular development and function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Loss of distinct arterial and venous boundaries in mice lacking endoglin, a vascular-specific TGFbeta coreceptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin-deficient mice, a unique model to study hereditary hemorrhagic telangiectasia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

A murine model of hereditary hemorrhagic telangiectasia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

TGF-beta receptors and signalling mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Clinical heterogeneity in hereditary haemorrhagic telangiectasia: are pulmonary arteriovenous malformations more common in families linked to endoglin?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin modulates cellular responses to TGF-beta 1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Mechanism of activation of the TGF-beta receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Molecular regulation of atrioventricular valvuloseptal morphogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

A histochemical analysis of polyanionic compounds found in the extracellular matrix encountered by migrating cephalic neural crest cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Protein extracts from early embryonic hearts initiate cardiac endothelial cytodifferentiation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Signal transduction of a tissue interaction during embryonic heart development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Appendix G: In Situ Hybridization: An Improved Whole-Mount Method for Xenopus Embryos

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

TGF-beta 3-mediated tissue interaction during embryonic heart development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Retroviral analysis of cardiac morphogenesis: discontinuous formation of coronary vessels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Structural development of endocardial cushions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Latrophilin-2 is a novel component of the epithelial-mesenchymal transition within the atrioventricular canal of the embryonic chicken heart.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Molecular markers of cardiac endocardial cushion development.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Transforming growth factor beta (TGFbeta ) signaling via differential activation of activin receptor-like kinases 2 and 5 during cardiac development. Role in regulating parasympathetic responsiveness

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

TGFbeta Type III and TGFbeta Type II receptors have distinct activities during epithelial-mesenchymal cell transformation in the embryonic heart.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Slug is an essential target of TGFbeta2 signaling in the developing chicken heart.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

TGFbeta2 and TGFbeta3 have separate and sequential activities during epithelial-mesenchymal cell transformation in the embryonic heart.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2001167

Cloning and developmental expression of the chick type II and type III TGF beta receptors

26 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Ultrastructure and three-dimensional organization of the telangiectases of hereditary hemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Antibodies to the Type II TGFbeta receptor block cell activation and migration during atrioventricular cushion transformation in the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Expression of adhesion molecules during the formation and differentiation of the avian endocardial cushion tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Embryonic endothelial cells transdifferentiate into mesenchymal cells expressing smooth muscle actins in vivo and in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Hereditary hemorrhagic telangiectasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Reduced angiogenic responses in adult Endoglin heterozygous mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Six novel mutations in the endoglin gene in hereditary hemorrhagic telangiectasia type 1 suggest a dominant-negative effect of receptor function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Regulation of ALK-1 signaling by the nuclear receptor LXRbeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Endoglin is expressed on human chondrocytes and forms a heteromeric complex with betaglycan in a ligand and type II TGFbeta receptor independent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Distribution of endoglin in early human development reveals high levels on endocardial cushion tissue mesenchyme during valve formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Slug is a mediator of epithelial-mesenchymal cell transformation in the developing chicken heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Fibulin-2 expression marks transformed mesenchymal cells in developing cardiac valves, aortic arch vessels, and coronary vessels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

TGF beta-mediated RhoA expression is necessary for epithelial-mesenchymal transition in the embryonic chick heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Production of the transforming growth factor-beta binding protein endoglin is regulated during chick heart development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

Cardiac endothelial heterogeneity defines valvular development as demonstrated by the diverse expression of JB3, an antigen of the endocardial cushion tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2006.12.038

10.1016/J.YDBIO.2006.12.038

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17250821%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference