(Q33743134)

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The new biology of ageing

scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

The new biology of ageing (English)

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Europe PubMed Central

29 July 2017

Linda Partridge

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Linda Partridge

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publication date

1 January 2010

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Europe PubMed Central

29 July 2017

number of pages

8

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based on heuristic

inferred from page(s)

Philosophical Transactions of the Royal Society B

1 reference

Europe PubMed Central

29 July 2017

365

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Europe PubMed Central

29 July 2017

1537

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Europe PubMed Central

29 July 2017

147-154

1 reference

Europe PubMed Central

29 July 2017

Caloric restriction delays disease onset and mortality in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The Target of Rapamycin pathway antagonizes pha-4/FoxA to control development and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

FOXO3A genotype is strongly associated with human longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

A theory of age-dependent mutation and senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

New model of health promotion and disease prevention for the 21st century

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Aging and survival: the genetics of life span extension by dietary restriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Quantitative evidence for conserved longevity pathways between divergent eukaryotic species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Toward a control theory analysis of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Insulin-like signaling, nutrient homeostasis, and life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Endocrine regulation of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Evolutionary conservation of regulated longevity assurance mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Caloric restriction in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Ruminations on dietary restriction and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Dietary restriction in aging nonhuman primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Opposing activities protect against age-onset proteotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Beyond the evolutionary theory of ageing, from functional genomics to evo-gero

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Caloric restriction and aging: controversial issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Hamilton's indicators of the force of selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Overview of caloric restriction and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Sex and death: what is the connection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Dietary restriction, mortality trajectories, risk and damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Evolutionary and mechanistic theories of aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The case for negative senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Demography of dietary restriction and death in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Extended longevity in mice lacking the insulin receptor in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Demography. Broken limits to life expectancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Mechanisms of ageing: public or private?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Keynote: mechanisms of senescence--complificationists versus simplificationists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Demography of longevity: past, present, and future trends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Why do life spans differ? Partitioning mean longevity differences in terms of age-specific mortality parameters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Evolution of lifespan in C. elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Extended life-span and stress resistance in the Drosophila mutant methuselah

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The genetics of caloric restriction in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Dwarf mice and the ageing process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

A C. elegans mutant that lives twice as long as wild type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Cytogerontology since 1881: a reappraisal of August Weismann and a review of modern progress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The moulding of senescence by natural selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842712

21 June 2018

Timing requirements for insulin/IGF-1 signaling in C. elegans

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Dynamics of the action of dFOXO on adult mortality in Drosophila.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Aging-dependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Mutations that increase the life span of C. elegans inhibit tumor growth.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Extended life-span conferred by cotransporter gene mutations in Drosophila.

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

A systematic look at an old problem

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Ageing: A lethal side-effect

1 reference

https://api.crossref.org/works/10.1098%2FRSTB.2009.0222

21 January 2018

Fitness cost of extended lifespan in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/20008392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1098/RSTB.2009.0222

1 reference

Europe PubMed Central

29 July 2017

release_oihwdfb6hrawlimvxzuvekjf4y

1 reference

https://api.fatcat.wiki/v0/release/oihwdfb6hrawlimvxzuvekjf4y

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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