(Q34773499)

4 August 2017

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title

The role of inflammation in the pathophysiology of CF lung disease (English)

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4 August 2017

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James F Chmiel

1

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4 August 2017

Melvin Berger

series ordinal

2

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4 August 2017

Michael W Konstan

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3

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4 August 2017

language of work or name

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1 August 2002

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Clinical Reviews in Allergy & Immunology

4 August 2017

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4 August 2017

23

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4 August 2017

1

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4 August 2017

5-27

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https://scigraph.springernature.com/pub.10.1385/criai:23:1:005

4 August 2017

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cites work

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12 December 2020

Inactivation of human bronchial mucosal proteinase inhibitor by Pseudomonas aeruginosa elastase

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12 December 2020

Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells

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12 December 2020

Progression of cystic fibrosis lung disease as a function of serum immunoglobulin G levels: a 5-year longitudinal study

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12 December 2020

Inhibition of human polymorphonuclear leukocyte cell responses by ibuprofen

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The lung in cystic fibrosis. A quantitative study including prevalence of pathologic findings among different age groups

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Aerosol α1 -antitrypsin treatment for cystic fibrosis

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12 December 2020

Hypogammaglobulinemia in patients with cystic fibrosis

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12 December 2020

Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis

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12 December 2020

Proinflammatory cytokine responses to P. aeruginosa infection in human airway epithelial cell lines

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12 December 2020

IL-10: evolving concepts

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12 December 2020

Inhibition of NF-kappaB activation and augmentation of IkappaBbeta by secretory leukocyte protease inhibitor during lung inflammation

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12 December 2020

Interleukin-8: an important chemoattractant in sputum of patients with chronic inflammatory airway diseases

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12 December 2020

Reduced IL-10 secretion by CD4+ T lymphocytes expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR).

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12 December 2020

Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures.

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12 December 2020

The role of cachectin/TNF in endotoxic shock and cachexia

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12 December 2020

Anti-inflammatory effects of mutant forms of secretory leukocyte protease inhibitor

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12 December 2020

Inflammatory cytokines in cystic fibrosis lungs

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12 December 2020

Evidence that Pseudomonas aeruginosa elastase does not inactivate the bronchial inhibitor in the presence of leukocyte elastase. Studies with cystic fibrosis sputum and with pure proteins

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12 December 2020

Lower respiratory infection and inflammation in infants with newly diagnosed cystic fibrosis

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12 December 2020

Regulation of epithelial sodium channels by the cystic fibrosis transmembrane conductance regulator.

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12 December 2020

Defective acidification of intracellular organelles in cystic fibrosis

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12 December 2020

Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

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12 December 2020

Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa

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12 December 2020

Effects of short-term inhaled fluticasone on oxidative burst of sputum cells in cystic fibrosis patients

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12 December 2020

Comparison of adherence of Pseudomonas aeruginosa to respiratory epithelial cells from cystic fibrosis patients and healthy subjects

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12 December 2020

Eicosapentaenoic acid in cystic fibrosis: evidence of a pathogenetic role for leukotriene B4

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12 December 2020

Gender differences in cystic fibrosis: Pseudomonas aeruginosa infection

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12 December 2020

Role of cystic fibrosis transmembrane conductance regulator in pulmonary clearance of Pseudomonas aeruginosa in vivo

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH.

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12 December 2020

Production of mucoid microcolonies by Pseudomonas aeruginosa within infected lungs in cystic fibrosis

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12 December 2020

Distinct sputum cytokine profiles in cystic fibrosis and other chronic inflammatory airway disease

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12 December 2020

The use of anti-inflammatory medications in cystic fibrosis: trends and physician attitudes

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12 December 2020

Exaggerated activation of nuclear factor-kappaB and altered IkappaB-beta processing in cystic fibrosis bronchial epithelial cells

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12 December 2020

Differential stimulation of cytosolic phospholipase A2 by bradykinin in human cystic fibrosis cell lines

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12 December 2020

Cystic fibrosis gene mutation (deltaF508) is associated with an intrinsic abnormality in Ca2+-induced arachidonic acid release by epithelial cells.

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12 December 2020

Alternate-day prednisone reduces morbidity and improves pulmonary function in cystic fibrosis.

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12 December 2020

Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis

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12 December 2020

Protease and elastase of Pseudomonas aeruginosa: inactivation of human plasma alpha 1-proteinase inhibitor

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12 December 2020

Potential mediator of inflammation. Phagocyte-derived oxidants suppress the elastase-inhibitory capacity of alpha 1-proteinase inhibitor in vitro

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12 December 2020

Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface

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12 December 2020

Stimulation of neutrophils by tumor necrosis factor

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12 December 2020

Diagnostic accuracy of oropharyngeal cultures in infants and young children with cystic fibrosis

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12 December 2020

Epithelial respiratory cells from cystic fibrosis patients do not possess specific Pseudomonas aeruginosa-adhesive properties

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12 December 2020

Quantitative evaluation of the development of tracheal submucosal glands in infants with cystic fibrosis and control infants

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12 December 2020

Surface expression of Fc gamma receptor III (CD16) on chemoattractant-stimulated neutrophils is determined by both surface shedding and translocation from intracellular storage compartments

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12 December 2020

Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells

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12 December 2020

Current understanding of the inflammatory process in cystic fibrosis: onset and etiology

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12 December 2020

Effect of high-dose ibuprofen in patients with cystic fibrosis.

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12 December 2020

Lower airway inflammation in infants and young children with cystic fibrosis.

1 reference

12 December 2020

Neutrophil elastase cleaves C3bi on opsonized pseudomonas as well as CR1 on neutrophils to create a functionally important opsonin receptor mismatch

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12 December 2020

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12 December 2020

The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis

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12 December 2020

In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.

1 reference

12 December 2020

Controlled Trial of Inhaled Budesonide in Patients with Cystic Fibrosis and Chronic BronchopulmonaryPseudomonas aeruginosaInfection

1 reference

12 December 2020

Cystic fibrosis: inflammatory response to infection with Burkholderia cepacia and Pseudomonas aeruginosa

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12 December 2020

Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function

1 reference

12 December 2020

Selective up-regulation of chemokine IL-8 expression in cystic fibrosis bronchial gland cells in vivo and in vitro

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12 December 2020

Overproduction of the CFTR R domain leads to increased levels of asialoGM1 and increased Pseudomonas aeruginosa binding by epithelial cells

1 reference

12 December 2020

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

12 December 2020

Novel Pseudomonas product stimulates interleukin-8 production in airway epithelial cells in vitro

1 reference

12 December 2020

Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections.

1 reference

12 December 2020

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

1 reference

12 December 2020

Altered respiratory epithelial cell cytokine production in cystic fibrosis

1 reference

12 December 2020

Excessive inflammatory response of cystic fibrosis mice to bronchopulmonary infection with Pseudomonas aeruginosa

1 reference

12 December 2020

Complement activation in cystic fibrosis respiratory fluids: in vivo and in vitro generation of C5a and chemotactic activity

1 reference

12 December 2020

CFTR as a cAMP-dependent regulator of sodium channels

1 reference

12 December 2020

IDENTIFICATION OF LEUKOTRIENES D AND B IN SPUTUM FROM CYSTIC FIBROSIS PATIENTS

1 reference

12 December 2020

Normal bronchial epithelial cells constitutively produce the anti-inflammatory cytokine interleukin-10, which is downregulated in cystic fibrosis

1 reference

12 December 2020

Management of pulmonary disease in patients with cystic fibrosis

1 reference

12 December 2020

The effects of the inhaled corticosteroid budesonide on lung function and bronchial hyperresponsiveness in adult patients with cystic fibrosis

1 reference

12 December 2020

Asialo GM1 is a receptor for Pseudomonas aeruginosa adherence to regenerating respiratory epithelial cells

1 reference

12 December 2020

Inflammation and infection in naive human cystic fibrosis airway grafts

1 reference

12 December 2020

Cross-sectional and longitudinal studies of naturally occurring antibodies to Pseudomonas aeruginosa in cystic fibrosis indicate absence of antibody-mediated protection and decline in opsonic quality after infection

1 reference

12 December 2020

Enhancement by tumor necrosis factor-alpha of Fc alpha receptor expression and IgA-mediated superoxide generation and killing of Pseudomonas aeruginosa by polymorphonuclear leukocytes

1 reference

12 December 2020

The genesis of cystic fibrosis lung disease

1 reference

12 December 2020

Pilot study to assess the effect of inhaled corticosteroids on lung function in patients with cystic fibrosis

1 reference

12 December 2020

Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients

1 reference

12 December 2020

Neutrophil elastase stimulates tracheal submucosal gland secretion that is inhibited by ICI 200,355

1 reference

12 December 2020

Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8

1 reference

12 December 2020

Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells

1 reference

12 December 2020

Nasal and bronchoalveolar lavage fluid cytokines in early cystic fibrosis

1 reference

12 December 2020

Inhibition of human polymorphonuclear leukocyte functions by ibuprofen

1 reference

12 December 2020

Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

1 reference

12 December 2020

Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor

1 reference

12 December 2020

Early pulmonary inflammation in infants with cystic fibrosis

1 reference

12 December 2020

Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung

1 reference

12 December 2020

Bronchoalveolar lavage findings in cystic fibrosis patients with stable, clinically mild lung disease suggest ongoing infection and inflammation

1 reference

12 December 2020

Inflammation in the lung in cystic fibrosis. A vicious cycle that does more harm than good?

1 reference

12 December 2020

Risk of persistent growth impairment after alternate-day prednisone treatment in children with cystic fibrosis

1 reference

12 December 2020

Lipid mediators in cystic fibrosis and chronic obstructive pulmonary disease

1 reference

12 December 2020

Functional differences between the 40 kDa and 50 to 70 kDa IgG Fc receptors on human neutrophils revealed by elastase treatment and antireceptor antibodies.

1 reference

12 December 2020

Functional IL-10 deficiency in the lung of cystic fibrosis (cftr(-/-)) and IL-10 knockout mice causes increased expression and function of B7 costimulatory molecules on alveolar macrophages

1 reference

12 December 2020

Randomised controlled trial of inhaled corticosteroids (fluticasone propionate) in cystic fibrosis

1 reference

12 December 2020

Reduction of ciliary beat frequency in vitro by sputum from patients with bronchiectasis: a serine proteinase effect

1 reference

12 December 2020

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line

1 reference

12 December 2020

Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis

1 reference

12 December 2020

Cystic fibrosis lung inflammation: early, sustained, and severe

1 reference

12 December 2020

Aerosolized prolastin suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection

1 reference

12 December 2020

Increased DNA levels in bronchoalveolar lavage fluid obtained from infants with cystic fibrosis

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12 December 2020

Cytokine dysregulation in activated cystic fibrosis (CF) peripheral lymphocytes

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12 December 2020

Prolonged inflammatory response to acute Pseudomonas challenge in interleukin-10 knockout mice.

1 reference

12 December 2020

High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.

1 reference

12 December 2020

Effect of human leukocyte enzymes on tracheal mucosa and its mucociliary activity

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12 December 2020

CFTR gene transfer reduces the binding of Pseudomonas aeruginosa to cystic fibrosis respiratory epithelium

1 reference

12 December 2020

Airway surface fluid volume and Cl content in cystic fibrosis and normal bronchial xenografts

1 reference

12 December 2020

Leukotriene B4 markedly elevated in the epithelial lining fluid of patients with cystic fibrosis

1 reference

12 December 2020

A multicenter study of alternate-day prednisone therapy in patients with cystic fibrosis. Cystic Fibrosis Foundation Prednisone Trial Group

1 reference

12 December 2020

IL-10 attenuates excessive inflammation in chronic Pseudomonas infection in mice

1 reference

12 December 2020

Qualitative and quantitative microbiological analysis of sputa of 102 patients with cystic fibrosis

1 reference

12 December 2020

Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis. A longitudinal study of immune complex activity and inflammatory response in sputum sol-phase of cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infections: influenc

1 reference

12 December 2020

Levels of free granulocyte elastase in bronchial secretions from patients with cystic fibrosis: effect of antimicrobial treatment against Pseudomonas aeruginosa

1 reference

12 December 2020

Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen

1 reference

12 December 2020

Receptors in the Pseudomonas aeruginosa adherence to injured and repairing airway epithelium

1 reference

12 December 2020

Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

1 reference

12 December 2020

Identifiers

DOI

10.1385/CRIAI:23:1:005

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Dimensions Publication ID

4 August 2017

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