(Q34816285)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

1 reference

title

Regulation of the transcriptional activity of the nuclear factor-kappaB p65 subunit (English)

1 reference

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12 November 2019

4

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12 November 2019

author name string

Linda Vermeulen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Gert De Wilde

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Sofie Notebaert

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Guy Haegeman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

1 September 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

published in

Biochemical Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

64

1 reference

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12 November 2019

issue

5-6

1 reference

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12 November 2019

page(s)

963-970

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

12 November 2019

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7 January 2021

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7 January 2021

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IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells

7 January 2021

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IkappaB family members function by different mechanisms

7 January 2021

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An N-terminal nuclear export signal is required for the nucleocytoplasmic shuttling of IkappaBalpha

7 January 2021

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A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes

7 January 2021

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The IKK complex: an integrator of all signals that activate NF-kappaB?

7 January 2021

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

7 January 2021

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I kappa B-independent control of NF-kappa B activity by modulatory phosphorylations

7 January 2021

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Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

7 January 2021

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Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

7 January 2021

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Activation of nuclear transcription factor NF-kappaB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit

7 January 2021

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

7 January 2021

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Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells

7 January 2021

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Ca2+/calmodulin-dependent protein kinase IV stimulates nuclear factor-kappa B transactivation via phosphorylation of the p65 subunit

7 January 2021

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The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

7 January 2021

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Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells

7 January 2021

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Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

7 January 2021

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Protein phosphatase 2A interacts with and directly dephosphorylates RelA

7 January 2021

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The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression

7 January 2021

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

7 January 2021

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

7 January 2021

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Induction of NF-kappaB by the Akt/PKB kinase

7 January 2021

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Wortmannin inhibits activation of nuclear transcription factors NF-kappaB and activated protein-1 induced by lipopolysaccharide and phorbol ester

7 January 2021

1 reference

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

7 January 2021

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Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

7 January 2021

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

7 January 2021

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Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

7 January 2021

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Kinase regulation in inflammatory response

7 January 2021

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A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

7 January 2021

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PDGF-induced Akt phosphorylation does not activate NF-kappa B in human vascular smooth muscle cells and fibroblasts

7 January 2021

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

7 January 2021

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

7 January 2021

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The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

7 January 2021

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RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)

7 January 2021

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Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor

7 January 2021

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Nuclear protein CBP is a coactivator for the transcription factor CREB

7 January 2021

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Phosphorylated CREB binds specifically to the nuclear protein CBP

7 January 2021

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Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

7 January 2021

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Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

7 January 2021

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Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator

7 January 2021

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Analysis of a cAMP-responsive activator reveals a two-component mechanism for transcriptional induction via signal-dependent factors

7 January 2021

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Transcription factor-specific requirements for coactivators and their acetyltransferase functions

7 January 2021

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The acetyltransferase activity of CBP stimulates transcription

7 January 2021

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The transcriptional coactivators p300 and CBP are histone acetyltransferases

7 January 2021

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MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells.

7 January 2021

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Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation

7 January 2021

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Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction

7 January 2021

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Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation

7 January 2021

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Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14.

7 January 2021

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Independent dynamic regulation of histone phosphorylation and acetylation during immediate-early gene induction

7 January 2021

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Translating the Histone Code

7 January 2021

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Chromatin disruption and modification

7 January 2021

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Signaling to chromatin through histone modifications

7 January 2021

1 reference

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The language of covalent histone modifications

7 January 2021

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Transcriptional regulation by the phosphorylation-dependent factor CREB

7 January 2021

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Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.

7 January 2021

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A transcriptional switch mediated by cofactor methylation

7 January 2021

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Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB.

7 January 2021

1 reference

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Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

7 January 2021

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Gene repression by coactivator repulsion

7 January 2021

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The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism

7 January 2021

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The transcription coactivator CBP is a dynamic component of the promyelocytic leukemia nuclear body

7 January 2021

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The promyelocytic (PML) nuclear compartment and transcription control

7 January 2021

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CREB-binding protein (CBP)/p300 and RNA polymerase II colocalize in transcriptionally active domains in the nucleus

7 January 2021

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The contribution of nuclear compartmentalization to gene regulation

7 January 2021

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Nuclear compartmentalization and gene activity

7 January 2021

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Subnuclear dynamics and transcription factor function.

7 January 2021

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Protein regulation: tag wrestling with relatives of ubiquitin

7 January 2021

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Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities

7 January 2021

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MAPK-regulated transcription: a continuously variable gene switch?

7 January 2021

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Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion

7 January 2021

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Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

7 January 2021

1 reference

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Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901161-9

Nuclear import of the Drosophila Rel protein Dorsal is regulated by phosphorylation

7 January 2021

1 reference

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Activation of human immunodeficiency virus transcription in T cells revisited: NF-kappaB p65 stimulates transcriptional elongation

7 January 2021

1 reference

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Human Elongator facilitates RNA polymerase II transcription through chromatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901161-9

Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event

7 January 2021

1 reference

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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

7 January 2021

1 reference

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Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter

7 January 2021

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Two waves of nuclear factor kappaB recruitment to target promoters

7 January 2021

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

7 January 2021

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Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor

7 January 2021

1 reference

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10.1016/S0006-2952(02)01161-9

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12213593%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference