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AMPK at the nexus of energetics and aging.
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Europe PubMed Central
PMCID
4287273
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
title
AMPK at the nexus of energetics and aging
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
author
William Mair
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3
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Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
author name string
Kristopher Burkewitz
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1
1 reference
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Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
Yue Zhang
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2
1 reference
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Europe PubMed Central
PMCID
4287273
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
publication date
10 April 2014
1 reference
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Europe PubMed Central
PMCID
4287273
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
published in
Cell Metabolism
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
volume
20
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
page(s)
10-25
1 reference
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Europe PubMed Central
PMCID
4287273
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
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Energy-dependent modulation of glucagon-like signaling in Drosophila via the AMP-activated protein kinase
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8 July 2018
AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans
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Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster
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8 July 2018
p70S6 kinase phosphorylates AMPK on serine 491 to mediate leptin's effect on food intake
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8 July 2018
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
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8 July 2018
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
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Short-term calorie restriction enhances skeletal muscle stem cell function
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8 July 2018
The ancient drug salicylate directly activates AMP-activated protein kinase
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8 July 2018
mTOR signaling in growth control and disease
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8 July 2018
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
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Deregulated MYC expression induces dependence upon AMPK-related kinase 5.
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8 July 2018
AMPK: a nutrient and energy sensor that maintains energy homeostasis
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8 July 2018
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
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8 July 2018
Diabetes, cancer, and metformin: connections of metabolism and cell proliferation
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8 July 2018
Autophagy links lipid metabolism to longevity in C. elegans
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8 July 2018
Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis
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8 July 2018
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.
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8 July 2018
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
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8 July 2018
Ageing: longevity hits a roadblock
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Autophagy and lipid metabolism coordinately modulate life span in germline-less C. elegans
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PubMed Central
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8 July 2018
AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Autophagy and aging
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8 July 2018
Calorie restriction: is AMPK a key sensor and effector?
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PubMed Central
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8 July 2018
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease
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PubMed Central
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8 July 2018
Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
TFEB links autophagy to lysosomal biogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan
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PubMed Central
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8 July 2018
A fluorescent reporter of AMPK activity and cellular energy stress
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8 July 2018
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
dFOXO-independent effects of reduced insulin-like signaling in Drosophila
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Fatty acid desaturation links germ cell loss to longevity through NHR-80/HNF4 in C. elegans
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Structure of mammalian AMPK and its regulation by ADP
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
A whole-organism screen identifies new regulators of fat storage
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
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PubMed Central
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8 July 2018
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Drosophila salt-inducible kinase (SIK) regulates starvation resistance through cAMP-response element-binding protein (CREB)-regulated transcription coactivator (CRTC).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
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8 July 2018
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
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PubMed Central
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8 July 2018
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
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8 July 2018
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
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8 July 2018
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
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8 July 2018
AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies
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8 July 2018
Life-long caloric restriction elicits pronounced protection of the aged myocardium: a role for AMPK.
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8 July 2018
DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
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8 July 2018
Signaling kinase AMPK activates stress-promoted transcription via histone H2B phosphorylation
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8 July 2018
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
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8 July 2018
Dietary restriction enhances germline stem cell maintenance
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8 July 2018
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
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8 July 2018
Extending healthy life span--from yeast to humans
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8 July 2018
The genetics of ageing
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8 July 2018
Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender
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8 July 2018
Metformin supplementation and life span in Fischer-344 rats
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8 July 2018
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle
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8 July 2018
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle
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8 July 2018
AMPK and SIRT1: a long-standing partnership?
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8 July 2018
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
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8 July 2018
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
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8 July 2018
Mammalian sirtuins: biological insights and disease relevance
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8 July 2018
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
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8 July 2018
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol
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8 July 2018
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
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PubMed Central
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8 July 2018
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply
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8 July 2018
4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
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8 July 2018
Ageing populations: the challenges ahead
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8 July 2018
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
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8 July 2018
Hot topics in aging research: protein translation, 2009.
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8 July 2018
A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation.
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8 July 2018
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
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8 July 2018
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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8 July 2018
AMPK in Health and Disease
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8 July 2018
Long-lived Indy and calorie restriction interact to extend life span.
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8 July 2018
Proteasomal regulation of the hypoxic response modulates aging in C. elegans
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8 July 2018
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
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8 July 2018
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
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8 July 2018
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
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8 July 2018
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.
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8 July 2018
Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans
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8 July 2018
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1
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8 July 2018
Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype
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8 July 2018
Fat metabolism links germline stem cells and longevity in C. elegans
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8 July 2018
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
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8 July 2018
AMPK and PPARdelta agonists are exercise mimetics
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8 July 2018
Dietary energy restriction modulates the activity of AMP-activated protein kinase, Akt, and mammalian target of rapamycin in mammary carcinomas, mammary gland, and liver
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8 July 2018
Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
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8 July 2018
AMPK phosphorylation of raptor mediates a metabolic checkpoint
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8 July 2018
Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice
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8 July 2018
Aging and survival: the genetics of life span extension by dietary restriction.
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8 July 2018
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
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8 July 2018
FoxO3 controls autophagy in skeletal muscle in vivo
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8 July 2018
Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
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8 July 2018
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
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8 July 2018
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans
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8 July 2018
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans
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8 July 2018
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
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8 July 2018
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
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8 July 2018
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
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8 July 2018
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
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8 July 2018
Two neurons mediate diet-restriction-induced longevity in C. elegans
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8 July 2018
Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis
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8 July 2018
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
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8 July 2018
Inflammation and metabolic disorders
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8 July 2018
Resveratrol improves health and survival of mice on a high-calorie diet
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8 July 2018
Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro
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8 July 2018
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
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8 July 2018
Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling
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8 July 2018
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
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8 July 2018
Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice
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8 July 2018
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.
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8 July 2018
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
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8 July 2018
Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes
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8 July 2018
Substrate-specific activation of sirtuins by resveratrol
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8 July 2018
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
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8 July 2018
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
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8 July 2018
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
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8 July 2018
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
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8 July 2018
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
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8 July 2018
TSC2 mediates cellular energy response to control cell growth and survival
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8 July 2018
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
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8 July 2018
TORCs: transducers of regulated CREB activity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Autophagy genes are essential for dauer development and life-span extension in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
A C. elegans mutant that lives twice as long as wild type
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
8 July 2018
Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Aspirin inhibits oxidant stress, reduces age-associated functional declines, and extends lifespan of Caenorhabditis elegans.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Metformin interacts with AMPK through binding to γ subunit.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMPK is a direct adenylate charge-regulated protein kinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
A gain-of-function screen identifies wdb and lkb1 as lifespan-extending genes in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Autophagy genes mediate the effect of calcineurin on life span in C. elegans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Down-regulation of AMP-activated protein kinase by calorie restriction in rat liver.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Metabolic adaptations to fasting and chronic caloric restriction in heart, muscle, and liver do not include changes in AMPK activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4287273
retrieved
26 October 2018
Neither LKB1 nor AMPK are the direct targets of metformin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24726383
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24726383
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CMET.2014.03.002
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
PMCID
4287273
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
PubMed ID
24726383
1 reference
stated in
Europe PubMed Central
PMCID
4287273
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24726383%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 March 2020
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