(Q34970862)

5 August 2017

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title

ER-associated degradation in protein quality control and cellular regulation (English)

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5 August 2017

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Randolph Y Hampton

1

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PubMed ID

12383799

5 August 2017

language of work or name

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1 August 2002

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Current Opinion in Cell Biology

5 August 2017

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5 August 2017

14

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5 August 2017

4

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5 August 2017

476-482

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Endoplasmic reticulum degradation. Reverse protein transport and its end in the proteasome

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Ubiquitin-mediated degradation of cellular proteins in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Molecular dissection of the role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

SEL1L, the human homolog of C. elegans sel-1: refined physical mapping, gene structure and identification of polymorphic markers

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Re-entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

A regulatory link between ER-associated protein degradation and the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

HRD gene dependence of endoplasmic reticulum-associated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Cdc48-Ufd1-Npl4: stuck in the middle with Ub.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The engagement of Sec61p in the ER dislocation process

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

ER-golgi traffic is a prerequisite for efficient ER degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Cod1p/Spf1p is a P-type ATPase involved in ER function and Ca2+ homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

An oxysterol-derived positive signal for 3-hydroxy- 3-methylglutaryl-CoA reductase degradation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

A 'distributed degron' allows regulated entry into the ER degradation pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Influence of molecular and chemical chaperones on protein folding

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Oligomerization state influences the degradation rate of 3-hydroxy-3-methylglutaryl-CoA reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900358-7

7 January 2021

10.1016/S0955-0674(02)00358-7

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12383799