(Q35853775)

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Functional links between telomeres and proteins of the DNA-damage response

scientific article published in August 2004

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Europe PubMed Central

10 August 2017

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Europe PubMed Central

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Functional links between telomeres and proteins of the DNA-damage response (English)

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stated in

Europe PubMed Central

10 August 2017

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Fabrizio d'Adda di Fagagna

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Fabrizio d'Adda di Fagagna

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Europe PubMed Central

10 August 2017

Stephen P Jackson

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Soo-Hwang Teo

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Europe PubMed Central

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15289453

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10 August 2017

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1 August 2004

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stated in

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

18

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stated in

Europe PubMed Central

10 August 2017

1781-1799

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stated in

Europe PubMed Central

10 August 2017

15

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stated in

Europe PubMed Central

10 August 2017

An alternative pathway for yeast telomere maintenance rescues est1- senescence

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A bouquet makes ends meet

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mouse models to study the role of telomeres in cancer, aging and DNA repair

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Cdc13 delivers separate complexes to the telomere for end protection and replication

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomeres and their control

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance is dependent on activities required for end repair of double-strand breaks.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Defying death after DNA damage.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A protein-counting mechanism for telomere length regulation in yeast.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Severe developmental defects, hypersensitivity to DNA-damaging agents, and lengthened telomeres in Arabidopsis MRE11 mutants

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere direction

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

NEJ1 prevents NHEJ-dependent telomere fusions in yeast without telomerase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Yeast telomeres exert a position effect on recombination between internal tracts of yeast telomeric DNA

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasia

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The DNA damage response: putting checkpoints in perspective

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance requires the RAD51D recombination/repair protein

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance by recombination in human cells.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku is associated with the telomere in mammals

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Interaction of human Ku70 with TRF2

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Plasma antioxidants from chocolate.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Disappearance of the telomere dysfunction-induced stress response in fully senescent cells.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Induction of telomerase activity by in vivo X-irradiation of mouse splenocytes and its possible role in chromosome healing

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

RAD50 function is essential for telomere maintenance in Arabidopsis.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Interfaces between the detection, signaling, and repair of DNA damage

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Subnuclear shuttling of human telomerase induced by transformation and DNA damage.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Rap1 affects the length and heterogeneity of human telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mammalian telomeres end in a large duplex loop

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Alternative lengthening of telomeres in mammalian cells

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A means to a DNA end: the many roles of Ku.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Senescence, apoptosis and therapy--cutting the lifelines of cancer.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Protection of telomeres by the Ku protein in fission yeast

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Quaternary structure of ATR and effects of ATRIP and replication protein A on its DNA binding and kinase activities

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Molecular characterization of inter-telomere and intra-telomere mutations in human ALT cells

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Elg1 forms an alternative PCNA-interacting RFC complex required to maintain genome stability

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The function of a stem-loop in telomerase RNA is linked to the DNA repair protein Ku.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Two modes of survival of fission yeast without telomerase.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance and cancer -- look, no telomerase.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

C. elegans clk-2, a gene that limits life span, encodes a telomere length regulator similar to yeast telomere binding protein Tel2p

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Rad51 recombinase and recombination mediators

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Inactivation of p53 results in high rates of homologous recombination

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku complex controls the replication time of DNA in telomere regions.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Functional conservation of the telomerase protein Est1p in humans

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Functional interaction between DNA-PKcs and telomerase in telomere length maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Human POT1 facilitates telomere elongation by telomerase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Identification of yeast mutants with altered telomere structure

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A novel protein activity mediates DNA binding of an ATR-ATRIP complex

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Living with genome instability: plant responses to telomere dysfunction

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku acts in a unique way at the mammalian telomere to prevent end joining

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Short telomeres induce a DNA damage response in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A DNA damage checkpoint response in telomere-initiated senescence

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The kinase activity of DNA-PK is required to protect mammalian telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The DNA-dependent protein kinase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance without telomerase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere maintenance and DNA replication: how closely are these two connected?

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Effects of double-strand break repair proteins on vertebrate telomere structure

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomere

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

t-loops at trypanosome telomeres.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Induction of telomerase activity by UV-irradiation in Chinese hamster cells

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Altering telomere structure allows telomerase to act in yeast lacking ATM kinases

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA damage foci at dysfunctional telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

TRF2 Protects Human Telomeres from End-to-End Fusions

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A short C-terminal domain of Yku70p is essential for telomere maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

H2AX regulates meiotic telomere clustering

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Strand-Specific Postreplicative Processing of Mammalian Telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Ku86 is essential in human somatic cells

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Oxidative stress shortens telomeres

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Mechanism and regulation of human non-homologous DNA end-joining

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

RPA regulates telomerase action by providing Est1p access to chromosome ends

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

MDC1/NFBD1: a key regulator of the DNA damage response in higher eukaryotes

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Sudden telomere lengthening triggers a Rad53-dependent checkpoint in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Linking histone deacetylation with the repair of DNA breaks

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere states and cell fates

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The yeast Xrs2 complex functions in S phase checkpoint regulation

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Accelerated telomere shortening in ataxia telangiectasia

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Chk1 and Chk2 kinases in checkpoint control and cancer

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA-PKcs is critical for telomere capping

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere looping permits gene activation by a downstream UAS in yeast

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Senescence Induced by Altered Telomere State, Not Telomere Loss

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The role of Schizosaccharomyces pombe Rad32, the Mre11 homologue, and other DNA damage response proteins in non-homologous end joining and telomere length maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Identification of Saccharomyces cerevisiae DNA ligase IV: involvement in DNA double-strand break repair

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Contribution of the Atm protein to maintaining cellular homeostasis evidenced by continuous activation of the AP-1 pathway in Atm-deficient brains

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Role of mammalian Rad54 in telomere length maintenance

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Pot1, the putative telomere end-binding protein in fission yeast and humans

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

The Ku Heterodimer Performs Separable Activities at Double-Strand Breaks and Chromosome Termini

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Molecular mechanism of nucleotide excision repair.

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Conserved structure for single-stranded telomeric DNA recognition

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Human CLK2 links cell cycle progression, apoptosis, and telomere length regulation

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

1 reference

5 June 2022

https://opencitations.net/index/coci/api/v1/references/10.1101/GAD.1214504

Identifiers

DOI

10.1101/GAD.1214504

1 reference

stated in

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

PubMed ID

15289453

retrieved

10 August 2017

(Q35853775)

Functional links between telomeres and proteins of the DNA-damage response

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