(Q36273884)

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Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis (English)

1 reference

Europe PubMed Central

13 August 2017

0 references

Harold L. Moses

7

object named as

H L Moses

1 reference

Europe PubMed Central

13 August 2017

author name string

R Serra

1

1 reference

Europe PubMed Central

13 August 2017

M Johnson

2

1 reference

Europe PubMed Central

13 August 2017

E H Filvaroff

3

1 reference

Europe PubMed Central

13 August 2017

J LaBorde

4

1 reference

Europe PubMed Central

13 August 2017

D M Sheehan

5

1 reference

Europe PubMed Central

13 August 2017

R Derynck

6

1 reference

Europe PubMed Central

13 August 2017

language of work or name

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publication date

1 October 1997

1 reference

Europe PubMed Central

13 August 2017

number of pages

12

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based on heuristic

inferred from page(s)

Journal of Cell Biology

1 reference

Europe PubMed Central

13 August 2017

139

1 reference

Europe PubMed Central

13 August 2017

2

1 reference

Europe PubMed Central

13 August 2017

541-552

1 reference

Europe PubMed Central

13 August 2017

Studies on the morphogenesis of the mouse sternum. I. Normal embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Bcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Regulation of differentiation by TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

A human chondrodysplasia due to a mutation in a TGF-beta superfamily member

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

What do BMPs do in mammals? Clues from the mouse short-ear mutation

1 reference

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30 September 2017

Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Responsiveness of articular cartilage from normal and inflamed mouse knee joints to various growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Toward a molecular understanding of skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

TGF-beta-receptor-mediated signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Molecular analysis of TGF beta signal transduction. Dominant-inhibitory mutations of the type II and type I TGF beta receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Growth factor actions on articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Chondrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-beta receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Transforming growth factor-beta 3 is required for secondary palate fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Role of transforming growth factor-beta in the development of the mouse embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

The biology of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

TGF-beta receptors and TGF-beta binding proteoglycans: recent progress in identifying their functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Role of transforming growth factor-beta in chondrogenic pattern formation in the embryonic limb: stimulation of mesenchymal condensation and fibronectin gene expression by exogenenous TGF-beta and evidence for endogenous TGF-beta-like activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Peptide growth factors and their interactions during chondrogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Bone growth: coordinating chondrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Formation of cartilage-like spheroids by micromass cultures of murine C3H10T1/2 cells upon treatment with transforming growth factor-beta 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

30 September 2017

Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Complete congenital sternal cleft in an adult: repair by autogenous tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Opposite effects of osteogenic protein and transforming growth factor beta on chondrogenesis in cultured long bone rudiments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Promotion of embryonic chick limb cartilage differentiation by transforming growth factor-beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

A rapid method for preparing high quality alizarin stained skeletons of adult mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Expression of TGF-beta isoforms during first trimester human embryogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Transforming growth factor-beta in calf articular cartilage organ cultures: synthesis and distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

29 June 2018

Autocrine or paracrine transforming growth factor-beta modulates the phenotype of chick embryo sternal chondrocytes in serum-free agarose culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

22 September 2018

Retinoic acid-induced stress protein synthesis in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2139797

22 September 2018

A dominant-negative receptor for type beta transforming growth factors created by deletion of the kinase domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritic human cartilage is more sensitive to transforming growth factor beta than is normal cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TGF-beta family and its composite receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of swelling, synovial hyperplasia and cartilage proteoglycan loss upon intra-articular injection of transforming growth factor beta-2 in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumoral calcinosis of the cervical spine in an infant. Case illustration

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of parathyroid hormone-related protein in rat articular cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth factors in experimental osteoarthritis: transforming growth factor beta pathogenic?

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to the N-terminal portion of cartilage-inducing factor A and transforming growth factor beta. Immunohistochemical localization and association with differentiating cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terminal differentiation of chondrocytes in culture is a spontaneous process and is arrested by transforming growth factor-beta 2 and basic fibroblast growth factor in synergy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of TGF-beta and c-fos mRNAs in the growth plates of developing human long bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/9334355

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.139.2.541

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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