(Q36375941)

English

CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

CD40 ligand (CD154) triggers a short-term CD4(+) T cell activation response that results in secretion of immunomodulatory cytokines and apoptosis (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

apoptotic process

0 references

T cell activation

1 reference

based on heuristic

inferred from title

11

object named as

June CH

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Blair PJ

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Riley JL

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Harlan DM

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Abe R

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Tadaki DK

5

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Hoffmann SC

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

White L

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Francomano T

8

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Perfetto SJ

9

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Kirk AD

10

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

0 references

publication date

1 February 2000

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

191

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

651-660

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CD40 ligand/trimer DNA enhances both humoral and cellular immune responses and induces protective immunity to infectious and tumor challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

The CD40-ligand stimulates T-lymphocytes via the neutral sphingomyelinase: a novel function of the CD40-ligand as signalling molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes. A gene therapy model for autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CD40L is important for induction of, but not response to, costimulatory activity. ICAM-1 as the second costimulatory molecule rapidly up-regulated by CD40L.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

The B7 and CD28 receptor families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

T-cell proliferation involving the CD28 pathway is associated with cyclosporine-resistant interleukin 2 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Emerging cytokine family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

The mechanism of action of cyclosporin A and FK506

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Activation of human dendritic cells through CD40 cross-linking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

30 September 2017

Involvement of CD40 ligand-CD40 and CTLA4-B7 pathways in murine acute graft-versus-host disease induced by allogeneic T cells lacking CD28.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

28 June 2018

The CD40 pathway in allograft rejection, acceptance, and tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

28 June 2018

Co-stimulation in T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

28 June 2018

Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

28 June 2018

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

Induction of allograft tolerance in the absence of Fas-mediated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

CD40 ligand signals optimize T helper cell cytokine production: role in Th2 development and induction of germinal centers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

Impaired induction of the apoptosis-protective protein Bcl-xL in activated PBMC from asymptomatic HIV-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

Patterns of virus burden and T cell phenotype are established early and are correlated with the rate of disease progression in human immunodeficiency virus type 1-infected persons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 September 2018

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

1 reference

https://api.crossref.org/works/10.1084%2FJEM.191.4.651

21 January 2018

CTLA4 signals are required to optimally induce allograft tolerance with combined donor-specific transfusion and anti-CD154 monoclonal antibody treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 October 2018

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 October 2018

https://api.crossref.org/works/10.1084%2FJEM.191.4.651

21 January 2018

Induction of B cell costimulatory function by recombinant murine CD40 ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195831

21 October 2018

CD40 ligand-transduced co-stimulation of T cells in the development of helper function

1 reference

https://api.crossref.org/works/10.1084%2FJEM.191.4.651

21 January 2018

Regulation of expression of the ligand for CD40 on T helper lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 preferentially costimulates activation of CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD40L (gp39)/CD40 in T/B cell interaction and primary immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accessory signaling by CD40 for T cell activation: induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A noncytolytic IL-10/Fc fusion protein prevents diabetes, blocks autoimmunity, and promotes suppressor phenomena in NOD mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a novel function of the CD40 ligand as a signalling molecule in T-lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-CD40 ligand antibody treatment of SNF1 mice with established nephritis: preservation of kidney function

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD28 co-stimulation stabilizes the expression of the CD40 ligand on T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a critical role for IL-2 in CD40-mediated activation of naive B cells by primary CD4 T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of CD154 (CD40 ligand) mRNA stability during T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of RNA binding proteins associated with CD40 ligand (CD154) mRNA turnover in human T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolongation of primate cardiac allograft survival by treatment with ANTI-CD40 ligand (CD154) antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/10684857

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.191.4.651

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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