(Q37298372)

19 August 2017

TGF-beta through Smad3 signaling stimulates vascular smooth muscle cell proliferation and neointimal formation (English)

1 reference

19 August 2017

Shirling Tsai

1

1 reference

19 August 2017

Scott T Hollenbeck

2

1 reference

19 August 2017

Evan J Ryer

3

1 reference

19 August 2017

Rachel Edlin

4

1 reference

19 August 2017

Dai Yamanouchi

5

1 reference

19 August 2017

Rishi Kundi

6

1 reference

19 August 2017

Chunjie Wang

7

1 reference

19 August 2017

Bo Liu

8

1 reference

19 August 2017

K Craig Kent

9

1 reference

19 August 2017

language of work or name

1 reference

12 June 2009

1 reference

American Journal of Physiology Heart and Circulatory Physiology

19 August 2017

1 reference

19 August 2017

297

1 reference

19 August 2017

2

1 reference

19 August 2017

H540-9

1 reference

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2724222/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor beta-induced downregulation of cyclin A in vascular smooth muscle cells

6 September 2017

1 reference

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Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase

6 September 2017

1 reference

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Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway

6 September 2017

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New insights into TGF-beta-Smad signalling

6 September 2017

1 reference

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

6 September 2017

1 reference

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Understanding p27(kip1) deregulation in cancer: down-regulation or mislocalization

6 September 2017

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Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

6 September 2017

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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

6 September 2017

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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

6 September 2017

1 reference

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Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

6 September 2017

1 reference

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Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

6 September 2017

1 reference

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p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

6 September 2017

1 reference

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Molecular mechanisms in intimal hyperplasia

6 September 2017

1 reference

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Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery

6 September 2017

1 reference

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Decreased type II/type I TGF-beta receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-beta1.

6 September 2017

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

6 September 2017

1 reference

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Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model

6 September 2017

1 reference

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Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes

6 September 2017

1 reference

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

6 September 2017

1 reference

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Principles of CDK regulation

6 September 2017

1 reference

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Vascular smooth muscle cells from injured rat aortas display elevated matrix production associated with transforming growth factor-beta activity

6 September 2017

1 reference

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Regulation of smooth muscle cell growth in injured artery

6 September 2017

1 reference

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Factors controlling the development of arterial lesions after injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Expression of transforming growth factor-beta 1 is increased in human vascular restenosis lesions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

PKCdelta is necessary for Smad3 expression and transforming growth factor beta-induced fibronectin synthesis in vascular smooth muscle cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells

28 September 2017

1 reference

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Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Transforming growth factor-beta-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent

28 September 2017

1 reference

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Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium.

26 June 2018

1 reference

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Two populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Protein kinase C delta induces apoptosis of vascular smooth muscle cells through induction of the tumor suppressor p53 by both p38-dependent and p38-independent mechanisms

2 September 2018

1 reference

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Extracellular matrix changes in stented human coronary arteries

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Transforming growth factor-beta-dependent events in vascular remodeling following arterial injury

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

TGF-beta stimulates collagen (I) in vascular smooth muscle cells via a short element in the proximal collagen promoter

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

The signaling protein Rho is necessary for vascular smooth muscle migration and survival but not for proliferation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

CCR2 deficiency decreases intimal hyperplasia after arterial injury

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724222

The expression of TGF-beta receptors in human atherosclerosis: evidence for acquired resistance to apoptosis due to receptor imbalance

2 September 2018

1 reference

12 December 2020

Differential effects of platelet-derived growth factor isotypes on human smooth muscle cell proliferation and migration are mediated by distinct signaling pathways

1 reference

12 December 2020

Targeted disruption of TGF-beta-Smad3 signaling leads to enhanced neointimal hyperplasia with diminished matrix deposition in response to vascular injury

1 reference

12 December 2020

Expression of cyclin-dependent kinase inhibitors in vascular disease

1 reference

12 December 2020

TGF-beta 1 induces the cyclin-dependent kinase inhibitor p27Kip1 mRNA and protein in murine B cells

1 reference

12 December 2020

Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer

1 reference

12 December 2020

Diverse Contribution of Bone Marrow Cells to Neointimal Hyperplasia After Mechanical Vascular Injuries

1 reference

12 December 2020

Transforming growth factor-beta inhibits human vascular smooth muscle cell growth and migration

1 reference

12 December 2020

Transforming growth factor-beta 1 inhibits human arterial smooth-muscle cell proliferation in a growth-rate-dependent manner

1 reference

12 December 2020

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

1 reference

12 December 2020

In vivo effect of TGF- beta 1. Enhanced intimal thickening by administration of TGF- beta 1 in rabbit arteries injured with a balloon catheter

1 reference

12 December 2020

10.1152/AJPHEART.91478.2007

Identifiers

DOI

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release_ffgdr3zpsjeljbb7tqrg3r5sbe

19 August 2017

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24 November 2022

mapped directly with Wikidata item

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19 August 2017

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