(Q37369504)

English

Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

scientific article published on July 1997

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin (English)

1 reference

Europe PubMed Central

20 August 2017

1 reference

based on heuristic

inferred from title

author name string

D A Waltz

1

1 reference

Europe PubMed Central

20 August 2017

L R Natkin

2

1 reference

Europe PubMed Central

20 August 2017

R M Fujita

3

1 reference

Europe PubMed Central

20 August 2017

Y Wei

4

1 reference

Europe PubMed Central

20 August 2017

H A Chapman

5

1 reference

Europe PubMed Central

20 August 2017

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

20 August 2017

Journal of Clinical Investigation

1 reference

Europe PubMed Central

20 August 2017

100

1 reference

Europe PubMed Central

20 August 2017

1

1 reference

Europe PubMed Central

20 August 2017

58-67

1 reference

Europe PubMed Central

20 August 2017

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Prevention of metastasis by inhibition of the urokinase receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Cytokines induce urokinase-dependent adhesion of human myeloid cells. A regulatory role for plasminogen activator inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Molecular evolution of plasminogen activator inhibitor-1 functional stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

The somatomedin B domain of vitronectin. Structural requirements for the binding and stabilization of active type 1 plasminogen activator inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

The plasminogen system and cell surfaces: evidence for plasminogen and urokinase receptors on the same cell type

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Vitronectin (serum spreading factor): its localisation in normal and fibrotic tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Novel purification of vitronectin from human plasma by heparin affinity chromatography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Plasminogen activation at the cell surface-matrix interface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

The plasminogen activator/plasmin system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Interactions between type 1 plasminogen activator inhibitor, extracellular matrix and vitronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Mapping of binding sites for heparin, plasminogen activator inhibitor-1, and plasminogen to vitronectin's heparin-binding region reveals a novel vitronectin-dependent feedback mechanism for the control of plasmin formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

6 September 2017

Cell-associated plasminogen activation: regulation and physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

14 September 2017

The directed migration of eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

14 September 2017

An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

14 September 2017

Regulation of integrin function by the urokinase receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Urokinase and urokinase receptor: a paracrine/autocrine system regulating cell migration and invasiveness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Receptor-mediated endocytosis of plasminogen activators and activator/inhibitor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Urokinase-type plasminogen activator and its receptor: new targets for anti-metastatic therapy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

28 September 2017

Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Urokinase and plasminogen activator inhibitor type 1 in pulmonary adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Binding of urokinase to its receptor promotes migration and invasion of human melanoma cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Cathepsin D-like aspartyl protease activity mediates the degradation of tissue-type plasminogen activator/plasminogen activator inhibitor-1 complexes in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Metastatic behavior of human melanoma cell lines in nude mice correlates with urokinase-type plasminogen activator, its type-1 inhibitor, and urokinase-mediated matrix degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

26 June 2018

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

2 September 2018

Urokinase receptor mediates mechanical force transfer across the cell surface.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=508165

2 September 2018

Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of Type 1 Plasminogen Activator Inhibitor and Vitronectin at Sites of Cellular Necrosis and Inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of elements of the plasminogen activation system in benign breast disease and breast cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of plasminogen activators and their inhibitors in human pancreatic carcinoma: immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor-like domain of urokinase in the experimental and spontaneous metastasis model

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the urokinase receptor as an adhesion receptor for vitronectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energetics of leukocyte integrin activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of Plasminogen Activators and Their Inhibitors in the Aortic Vessel Wall in Relation to the Presence and Severity of Atherosclerotic Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited plasmin proteolysis of vitronectin. Characterization of the adhesion protein as morpho-regulatory and angiostatin-binding factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired wound healing in mice with a disrupted plasminogen gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase receptor is a major vitronectin-binding protein on endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase receptor antagonists inhibit angiogenesis and primary tumor growth in syngeneic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoelectron-microscopic localization of S-protein/vitronectin in human atherosclerotic wall

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depressed bronchoalveolar urokinase activity in patients with adult respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmin cleavage of vitronectin Identification of the site and consequent attenuation in binding plasminogen activator inhibitor-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Limited proteolysis of vitronectin by plasmin destroys heparin binding activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator system in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of cell surface-bound plasmin by cell-associated urokinase-type or secreted tissue-type plasminogen activator: a key event in melanoma cell invasiveness in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic peptides derived from the sequence around the plasmin cleavage site in vitronectin. Use in mapping the PAI-1 binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain structure of vitronectin. Alignment of active sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9202057

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI119521

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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