(Q37500527)

English

Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs.

scientific article published on September 2009

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29 January 2020

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Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs (English)

1 reference

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29 January 2020

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Lorraine J. Gudas

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Lorraine J Gudas

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29 January 2020

Kymora B Scotland

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Kymora B Scotland

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29 January 2020

Vasundhra Kashyap

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Vasundhra Kashyap

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Naira C Rezende

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29 January 2020

Sebastian M Shaffer

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1 September 2009

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Stem Cells and Development

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1093-1108

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29 January 2020

Analysis of Rex1 (zfp42) function in embryonic stem cell differentiation

1 reference

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23 August 2017

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

1 reference

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23 August 2017

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

1 reference

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23 August 2017

Klf4 reverts developmentally programmed restriction of ground state pluripotency

1 reference

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23 August 2017

Epidermal homeostasis: a balancing act of stem cells in the skin

1 reference

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23 August 2017

Oct4-induced pluripotency in adult neural stem cells.

1 reference

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23 August 2017

The miR-302-367 cluster as a potential stemness regulator in ESCs

1 reference

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Profiling RE1/REST-mediated histone modifications in the human genome

1 reference

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23 August 2017

MicroRNAs: target recognition and regulatory functions

1 reference

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23 August 2017

MicroRNAs: key regulators of stem cells

1 reference

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23 August 2017

The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

1 reference

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23 August 2017

Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells

1 reference

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23 August 2017

Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells

1 reference

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23 August 2017

EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency

1 reference

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23 August 2017

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

1 reference

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23 August 2017

Rest-mediated regulation of extracellular matrix is crucial for neural development

1 reference

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23 August 2017

The growth factor environment defines distinct pluripotent ground states in novel blastocyst-derived stem cells

1 reference

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23 August 2017

Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

1 reference

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23 August 2017

NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma

1 reference

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23 August 2017

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

1 reference

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23 August 2017

REST regulates distinct transcriptional networks in embryonic and neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

1 reference

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23 August 2017

Generation of mouse induced pluripotent stem cells without viral vectors

1 reference

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23 August 2017

The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer

1 reference

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23 August 2017

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

1 reference

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23 August 2017

Stochasticity and the molecular mechanisms of induced pluripotency

1 reference

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23 August 2017

Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis

1 reference

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23 August 2017

Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter

1 reference

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23 August 2017

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

1 reference

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23 August 2017

Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells

1 reference

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23 August 2017

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

1 reference

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23 August 2017

Pluripotent stem cell lines

1 reference

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23 August 2017

Genome-scale DNA methylation maps of pluripotent and differentiated cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes

1 reference

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23 August 2017

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

1 reference

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23 August 2017

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

1 reference

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23 August 2017

Reprogramming of pancreatic beta cells into induced pluripotent stem cells

1 reference

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23 August 2017

Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos

1 reference

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23 August 2017

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

1 reference

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23 August 2017

The ground state of embryonic stem cell self-renewal

1 reference

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23 August 2017

Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells

1 reference

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23 August 2017

DNA methylation landscapes: provocative insights from epigenomics

1 reference

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23 August 2017

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

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23 August 2017

Requirement of Nanog dimerization for stem cell self-renewal and pluripotency

1 reference

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23 August 2017

Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells

1 reference

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23 August 2017

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

1 reference

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23 August 2017

Module map of stem cell genes guides creation of epithelial cancer stem cells

1 reference

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23 August 2017

REST maintains self-renewal and pluripotency of embryonic stem cells

1 reference

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23 August 2017

An extended transcriptional network for pluripotency of embryonic stem cells

1 reference

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23 August 2017

A glimpse into the epigenetic landscape of gene regulation

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Selective blockade of microRNA processing by Lin28

1 reference

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23 August 2017

Stem cell regulation by polycomb repressors: postponing commitment

1 reference

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23 August 2017

Generation of human induced pluripotent stem cells from dermal fibroblasts

1 reference

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23 August 2017

Generation of pluripotent stem cells from adult mouse liver and stomach cells

1 reference

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23 August 2017

Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors

1 reference

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23 August 2017

Reprogramming of human somatic cells to pluripotency with defined factors

1 reference

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23 August 2017

Nanog safeguards pluripotency and mediates germline development

1 reference

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23 August 2017

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

1 reference

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23 August 2017

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

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23 August 2017

Induced pluripotent stem cell lines derived from human somatic cells

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23 August 2017

MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells

1 reference

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23 August 2017

Producing primate embryonic stem cells by somatic cell nuclear transfer.

1 reference

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23 August 2017

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

1 reference

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23 August 2017

Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog

1 reference

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23 August 2017

MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1.

1 reference

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23 August 2017

"Destemming" cancer stem cells

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23 August 2017

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

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23 August 2017

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

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23 August 2017

Successful co-immunoprecipitation of Oct4 and Nanog using cross-linking

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23 August 2017

Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells

1 reference

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23 August 2017

Diverse actions of retinoid receptors in cancer prevention and treatment.

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23 August 2017

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

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23 August 2017

Derivation of pluripotent epiblast stem cells from mammalian embryos

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23 August 2017

New cell lines from mouse epiblast share defining features with human embryonic stem cells

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23 August 2017

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

1 reference

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23 August 2017

High-resolution profiling of histone methylations in the human genome

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23 August 2017

Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1

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23 August 2017

DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

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23 August 2017

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development

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23 August 2017

Epigenetic signatures of stem-cell identity.

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23 August 2017

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

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23 August 2017

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

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23 August 2017

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Epigenetic stem cell signature in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

A protein interaction network for pluripotency of embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The genomic landscape of histone modifications in human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Cancer stem cells: models and concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Screening for genes essential for mouse embryonic stem cell self-renewal using a subtractive RNA interference library

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

DExD/H box RNA helicases: multifunctional proteins with important roles in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Sall4 interacts with Nanog and co-occupies Nanog genomic sites in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Dissecting self-renewal in stem cells with RNA interference

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Regulation of the pluripotency marker Rex-1 by Nanog and Sox2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Control of developmental regulators by Polycomb in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Polycomb complexes repress developmental regulators in murine embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Chromatin signatures of pluripotent cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Differentiation of mouse embryonic stem cells after RNA interference-mediated silencing of OCT4 and Nanog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Increased expression of the polycomb group gene, EZH2, in transitional cell carcinoma of the bladder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The Polycomb group protein EZH2 directly controls DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Core transcriptional regulatory circuitry in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Transcriptional regulation of nanog by OCT4 and SOX2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

High-efficiency RNA interference in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Expression of transcription factor Oct-4 and other embryonic genes in CD133 positive cells from human umbilical cord blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Histone code modifications on pluripotential nuclei of reprogrammed somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The transcriptome profile of human embryonic stem cells as defined by SAGE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Gene repression by Polycomb group protein complexes: a distinct complex for every occasion?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Embryonic stem cell-specific MicroRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Multipotent cell lineages in early mouse development depend on SOX2 function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Preimplantation human embryos and embryonic stem cells show comparable expression of stage-specific embryonic antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Translating the Histone Code

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The polycomb-group gene Ezh2 is required for early mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Targeted disruption of mouse Yin Yang 1 transcription factor results in peri-implantation lethality.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Embryonic stem cell lines derived from human blastocysts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Viable offspring derived from fetal and adult mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zfp-42) in F9 teratocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The octamer motif present in the Rex-1 promoter binds Oct-1 and Oct-3 expressed by EC cells and ES cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Establishment in culture of pluripotential cells from mouse embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

The protein Id: a negative regulator of helix-loop-helix DNA binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

23 August 2017

Transcription factor YY1 functions as a PcG protein in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Developmental biology. Pluripotent chromatin state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

STAT3 and Oct-3/4 control histone modification through induction of Eed in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Hierarchical recruitment of polycomb group silencing complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Unique gene expression signatures of independently-derived human embryonic stem cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Stem cells. Setting standards for human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

14 September 2017

An analysis of retinoic acid-induced gene expression and metabolism in AB1 embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

28 September 2017

Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

28 September 2017

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

Chromatin remodeling during mouse and human embryonic stem cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

26 June 2018

Is REST a regulator of pluripotency?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Is REST required for ESC pluripotency?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFkappaB and cooperating with Stat3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Induction of pluripotent stem cells from fibroblast cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Developmental regulation of Eed complex composition governs a switch in global histone modification in brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Nanog promotes transfer of pluripotency after cell fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Silencing of the gene for the beta subunit of human chorionic gonadotropin by the embryonic transcription factor Oct-3/4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 September 2018

Expression of transcriptional factor Oct-4 and other embryonic genes in CD133 positive cells from human umbilical cord blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

2 October 2018

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3135180

3 December 2018

Distinctive nuclear organisation of centromeres and regions involved in pluripotency in human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19480567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BMP4 initiates human embryonic stem cell differentiation to trophoblast

1 reference

https://pubmed.ncbi.nlm.nih.gov/19480567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Periodic Activation of Wnt/β-Catenin Signaling Enhances Somatic Cell Reprogramming Mediated by Cell Fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19480567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19480567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem Cells and Cancer: Two Faces of Eve

1 reference

https://pubmed.ncbi.nlm.nih.gov/19480567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/SCD.2009.0113

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19480567%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19480567%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19480567%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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