(Q37856372)

24 August 2017

1 reference

title

A longer and healthier life with TOR down-regulation: genetics and drugs (English)

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24 August 2017

2

Linda Partridge

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Ivana Bjedov

object named as

Ivana Bjedov

series ordinal

1

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publication date

1 April 2011

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Biochemical Society Transactions

24 August 2017

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24 August 2017

39

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24 August 2017

2

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24 August 2017

460-465

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Extending healthy life span--from yeast to humans

24 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

21 January 2018

The genetics of ageing

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

TOR signaling in growth and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Functions and regulation of the 70kDa ribosomal S6 kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Molecular mechanisms of mTOR-mediated translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

TOR-dependent control of autophagy: biting the hand that feeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

TOR complex 2: a signaling pathway of its own.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

TOR and ageing: a complex pathway for a complex process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

The pharmacology of mTOR inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Growth stimulation leads to cellular senescence when the cell cycle is blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

The multiple facets of mTOR in immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Immune regulation by rapamycin: moving beyond T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Translational control of the innate immune response through IRF-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Immunology: A metabolic switch to memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Inflamm-ageing and lifelong antigenic load as major determinants of ageing rate and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Can autophagy promote longevity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Fat metabolism links germline stem cells and longevity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

mTOR and the control of whole body metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Mitochondrial signaling, TOR, and life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Broad spectrum detoxification: the major longevity assurance process regulated by insulin/IGF-1 signaling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Cell stress and aging: new emphasis on multiplex resistance mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Translational responses to growth factors and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Stressin' Sestrins take an aging fight

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Genetic links between diet and lifespan: shared mechanisms from yeast to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

Aging and survival: the genetics of life span extension by dietary restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

RAG GTPases in nutrient-mediated TOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390460

21 January 2018

Identifiers

DOI

10.1042/BST0390460

1 reference

24 August 2017

1 reference

PubMed ID

21428920