(Q40139474)

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Epidermal growth factor and transforming growth factor-beta1 enhance HK-2 cell migration through a synergistic increase of matrix metalloproteinase and sustained activation of ERK signaling pathway

scientific article published on 30 March 2007

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scholarly article

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Europe PubMed Central

17 September 2017

Epidermal growth factor and transforming growth factor-beta1 enhance HK-2 cell migration through a synergistic increase of matrix metalloproteinase and sustained activation of ERK signaling pathway (English)

1 reference

Europe PubMed Central

17 September 2017

author name string

Ya-Chung Tian

1

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Europe PubMed Central

17 September 2017

Yung-Chang Chen

2

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Europe PubMed Central

17 September 2017

Chiz-Tzung Chang

3

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Europe PubMed Central

17 September 2017

Cheng-Chieh Hung

4

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Europe PubMed Central

17 September 2017

Mai-Szu Wu

5

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Europe PubMed Central

17 September 2017

Aled Phillips

6

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17 September 2017

Chih-Wei Yang

7

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17 September 2017

language of work or name

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publication date

30 March 2007

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Europe PubMed Central

17 September 2017

Experimental Cell Research

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17 September 2017

313

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17 September 2017

11

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Europe PubMed Central

17 September 2017

2367-2377

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Europe PubMed Central

17 September 2017

Significance of tubulointerstitial changes in the renal cortex for the excretory function and concentration ability of the kidney: a morphometric contribution

1 reference

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Epithelial-mesenchymal transition and its implications for fibrosis

1 reference

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Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

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The role of epithelial-to-mesenchymal transition in renal fibrosis

1 reference

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Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration

1 reference

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Leptospiral outer membrane protein induces extracellular matrix accumulation through a TGF-beta1/Smad-dependent pathway.

1 reference

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TGF-beta1-mediated inhibition of HK-2 cell migration

1 reference

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Expression of transforming growth factor-beta isoforms in human glomerular diseases

1 reference

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Ligand activation of overexpressed epidermal growth factor receptor results in colony dissociation and disturbed E-cadherin function in HSC-1 human cutaneous squamous carcinoma cells

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

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Interaction between the transforming growth factor-beta type II receptor/Smad pathway and beta-catenin during transforming growth factor-beta1-mediated adherens junction disassembly

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Integrity of cell-cell contacts is a critical regulator of TGF-beta 1-induced epithelial-to-myofibroblast transition: role for beta-catenin

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Transforming growth factor-beta and epidermal growth factor synergistically stimulate epithelial to mesenchymal transition (EMT) through a MEK-dependent mechanism in primary cultured pig thyrocytes.

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Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats.

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

1 reference

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Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

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Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation

1 reference

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HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney

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Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.

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Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Multiple positive and negative regulators of signaling by the EGF-receptor

1 reference

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The MAPK signaling cascade

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Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells

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Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation

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Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5

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Matrix Metalloproteinase-9 Silencing by RNA Interference Triggers the Migratory-adhesive Switch in Ewing's Sarcoma Cells

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Tales from the crypt[ic] sites of the extracellular matrix

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Extracellular matrix and integrin signalling: the shape of things to come

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Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes

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10.1016/J.YEXCR.2007.03.022

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Europe PubMed Central

17 September 2017

release_s54h7gghwvf4zabls2bngnyxy4

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Europe PubMed Central

17 September 2017

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