(Q408186)

English

Kynureninase

mammalian protein found in Homo sapiens

kynureninase
KYNU
L-kynurenine hydrolase

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16719

Pyridoxal phosphate-dependent transferase, major domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16719

Pyridoxal phosphate-dependent transferase domain 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16719

Pyridoxal phosphate-dependent transferase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16719

Aminotransferase class V domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein homodimerization activity

determination method

1 reference

8 April 2019

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

kynureninase activity

determination method

7 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

16 July 2018

Cloning and recombinant expression of rat and human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

catalytic activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

3-hydroxykynureninase activity

determination method

1 reference

8 April 2019

NAD Deficiency, Congenital Malformations, and Niacin Supplementation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

kynureninase activity

determination method

8 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

Cloning and recombinant expression of rat and human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

kynureninase activity

determination method

7 references

8 April 2019

Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Cloning and recombinant expression of rat and human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

determination method

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Intracellular localization and characterization of 3-hydroxykynureninase in human liver

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

determination method

1 reference

8 April 2019

Intracellular localization and characterization of 3-hydroxykynureninase in human liver

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

determination method

2 references

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

biological process

pyridine nucleotide biosynthetic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

response to vitamin B6

determination method

1 reference

8 April 2019

High-performance liquid chromatographic assay of human lymphocyte kynureninase activity levels

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

response to interferon-gamma

determination method

1 reference

8 April 2019

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

tryptophan catabolic process to acetyl-CoA

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

L-kynurenine catabolic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

tryptophan catabolic process

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Xanthurenic aciduria due to a mutation in KYNU encoding kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

quinolinate biosynthetic process

determination method

1 reference

27 March 2018

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

anthranilate metabolic process

determination method

1 reference

27 March 2018

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16719&geneProductId=UniProtKB:Q16719

determination method

NAD biosynthetic process

determination method

tryptophan catabolic process to kynurenine

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

'de novo' NAD biosynthetic process from tryptophan

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

anthranilate metabolic process

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Purification and biochemical characterization of some of the properties of recombinant human kynureninase

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16719

determination method

http://purl.uniprot.org/uniprot/Q16719

1 reference

Identifiers.org

Aminotransferase class V domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q16719

Commons category

Kynureninase

0 references

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000264170

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000264170

ENSP00000364928

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000364928

ENSP00000386731

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386731

ENSP00000387296

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000387296

ENSP00000401190

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000401190

ENSP00000481930

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000481930

ENSP00000482009

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000482009

ENSP00000484801

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000484801

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

Sitelinks

Wikipedia(11 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:Kynureninase

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