(Q41172359)

27 September 2017

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title

Clinical pharmacokinetics of vinorelbine (English)

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27 September 2017

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D Levêque

1

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PubMed ID

8877249

27 September 2017

F Jehl

series ordinal

2

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27 September 2017

1 September 1996

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Clinical Pharmacokinetics

27 September 2017

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27 September 2017

31

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27 September 2017

3

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27 September 2017

184-197

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https://scigraph.springernature.com/pub.10.2165/00003088-199631030-00003

27 September 2017

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cites work

Determination of vinorelbine (Navelbine) in tumour cells by high-performance liquid chromatography

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12 December 2020

Metabolism of the Catharanthus alkaloids: from Streptomyces griseus to monoamine oxidase B.

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12 December 2020

Phase-II study of Navelbine in advanced breast cancer

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Clinical pharmacokinetics of vinorelbine alone and combined with cisplatin

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Oral vinzolidine as therapy for Kaposi's sarcoma and carcinomas of lung, breast, and colon/rectum

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Vinorelbine as first-line chemotherapy for metastatic breast carcinoma

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Pharmacokinetics of vincristine in children and adolescents with acute lymphocytic leukemia

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12 December 2020

Radioimmunoassay and preliminary pharmacokinetic studies in rats of 5'-noranhydrovinblastine (navelbine)

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12 December 2020

Mechanism of inhibition of cell proliferation by Vinca alkaloids.

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12 December 2020

Pharmacokinetics of navelbine after oral administration in cancer patients

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12 December 2020

The action of vincaleukoblastine on mitosis in vitro

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The pharmacokinetics of [3H]-vincristine in man

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12 December 2020

High-performance liquid chromatographic determination of navelbine in MO4 mouse fibrosarcoma cells and biological fluids

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12 December 2020

Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis

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12 December 2020

Determination of navelbine and desacetylnavelbine in biological fluids by high-performance liquid chromatography

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12 December 2020

Relative bioavailability of two oral formulations of navelbine in cancer patients

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12 December 2020

Pulmonary distribution of vinorelbine in patients with non-small-cell lung cancer

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12 December 2020

Intravenous vinorelbine as first-line and second-line therapy in advanced breast cancer

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12 December 2020

ORAL ADMINISTRATION OF VINBLASTINE SULFATE (NSC-49842) TO CANCER PATIENTS

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Clinical pharmacokinetics of the antitumor drug navelbine (5'-noranhydrovinblastine)

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12 December 2020

The pharmacokinetics of 4-acetyl tritium vinblastine in two patients

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12 December 2020

Human liver microsomal cytochrome P450 3A isozymes mediated vindesine biotransformation. Metabolic drug interactions

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12 December 2020

Phase II trial of vinorelbine/doxorubicin as first-line therapy of advanced breast cancer

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12 December 2020

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

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12 December 2020

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

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12 December 2020

P-glycoprotein mediated resistance to 5'-nor-anhydro-vinblastine (Navelbine)

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12 December 2020

A comparative randomized trial of vinca alkaloids in patients with metastatic breast carcinoma

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Accumulation and release of vinblastine and vincristine by HeLa cells: light microscopic, cinematographic, and biochemical study

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12 December 2020

Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of a European multicenter trial including 612 patients

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12 December 2020

Determination of vinorelbine in rabbit plasma by high-performance liquid chromatography with coulometric detection

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12 December 2020

Oral vinblastine sulfate in Hodgkin's disease

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12 December 2020

In situ selection of a human rhabdomyosarcoma resistant to vincristine with altered beta-tubulins.

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The discovery of the vinca alkaloids--chemotherapeutic agents against cancer

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12 December 2020

Oral vinorelbine (Navelbine) in the treatment of advanced breast cancer.

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12 December 2020

Pharmacokinetics of vinorelbine in man.

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12 December 2020

Phase II trial of weekly intravenous vinorelbine in first-line advanced breast cancer chemotherapy

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12 December 2020

Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers

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12 December 2020

Bio-analysis of vinorelbine by high-performance liquid chromatography with fluorescence detection

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12 December 2020

Cellular uptake and tubulin binding properties of four Vinca alkaloids

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12 December 2020

Myeloperoxidase: an enzyme involved in intrinsic vincristine resistance in human myeloblastic leukemia.

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12 December 2020

Vinorelbine: a horse of a different color?

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12 December 2020

Pharmacokinetics and metabolism of Navelbine

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12 December 2020

Pharmacokinetic profile of vinorelbine, a new semi-synthetic vinca alkaloid, determined by high-performance liquid chromatography

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12 December 2020

Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study.

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12 December 2020

Structure-activity relationships of dimeric Catharanthus alkaloids. 1. Deacetyl vinblastine amide (vindesine) sulfate

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12 December 2020

Randomized comparison of vinorelbine and melphalan in anthracycline-refractory advanced breast cancer

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12 December 2020

Summary of data from in vitro and phase I vinorelbine (Navelbine) studies.

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12 December 2020

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

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12 December 2020

Vinorelbine: a novel vinca alkaloid.

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12 December 2020

Experimental antitumor activity of Navelbine

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12 December 2020

Vinorelbine. A review of its pharmacological properties and clinical use in cancer chemotherapy

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12 December 2020

Elimination of permeability mutants from selections for drug resistance in mammalian cells

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12 December 2020

Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions

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12 December 2020

Immunofluorescence study of the action of navelbine, vincristine and vinblastine on mitotic and axonal microtubules

1 reference

12 December 2020

[Characterization of the mechanism of cross-resistance to vinca alkaloids and taxoids in the human J82 bladder tumor cell line]

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12 December 2020

A Phase II Study of Navelbine (Vinorelbine) in the Treatment of Non-Small-Cell Lung Cancer

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12 December 2020

Vinorelbine high-affinity binding to human platelets and lymphocytes: distribution in human blood

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12 December 2020

Oral administration of [3H]navelbine in patients: comparative pharmacokinetics using radioactive and radioimmunologic determination methods

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12 December 2020

Phase II trial of vinorelbine in metastatic squamous cell esophageal carcinoma. European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group

1 reference

12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

12 December 2020

Phase II trial of vinzolidine, an oral vinca alkaloid, in Hodgkin's disease and non-Hodgkin's lymphoma

1 reference

12 December 2020

High-performance liquid chromatographic determination of navelbine in human plasma and urine

1 reference

12 December 2020

Biliary elimination and pharmacokinetics of vinorelbine in micropigs

1 reference

12 December 2020

The Response of Hodgkin's Disease to Treatment with Oral Vinblastine Sulfate

1 reference

12 December 2020

Differential activity of vincristine and vinblastine against cultured cells

1 reference

12 December 2020

Comparative pharmacokinetics of antitumor Vinca alkaloids: intravenous bolus injections of navelbine and related alkaloids to cancer patients and rats

1 reference

12 December 2020

Correlation of biologic data with physico-chemical properties among the Vinca alkaloids and their congeners

1 reference

12 December 2020

P-glycoprotein: its role in drug resistance

1 reference

12 December 2020

Cytotoxic thresholds of vincristine in a murine and a human leukemia cell line in vitro

1 reference

12 December 2020

Differential cellular retention of vincristine and vinblastine by cultured human promyelocytic leukemia HL-60/Cl cells: the basis of differential toxicity

1 reference

12 December 2020

Resistance to antimitotic agents as genetic probes of microtubule structure and function

1 reference

12 December 2020

Pharmacokinetic and preliminary metabolic fate of navelbine in humans as determined by high performance liquid chromatography

1 reference

12 December 2020

The clinical pharmacokinetics of vinorelbine (Navelbine)

1 reference

12 December 2020

Multicenter phase II study of weekly oral vinorelbine for stage IV non-small-cell lung cancer

1 reference

12 December 2020

Pharmacokinetics of a new anticancer drug, navelbine, in patients. Comparative study of radioimmunologic and radioactive determination methods

1 reference

12 December 2020

Phase I/II trial of continuous infusion vinorelbine for advanced breast cancer

1 reference

12 December 2020

[Pharmacology of Catharanthus alkaloids]

1 reference

12 December 2020

Pharmacokinetic, bioavailability, and feasibility study of oral vinorelbine in patients with solid tumors

1 reference

12 December 2020

Verapamil reversal of vincristine resistance and cross-resistance patterns of vincristine-resistant Chinese hamster ovary cells

1 reference

12 December 2020

10.2165/00003088-199631030-00003

Identifiers

DOI

1 reference

PubMed ID

8877249

Dimensions Publication ID

27 September 2017

0 references

1 reference

PubMed ID

8877249