(Q44999245)

8 December 2017

Lipid rafts mediate the synaptic localization of alpha-synuclein (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

1 reference

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Doris L Fortin

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

Matthew D Troyer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

Ken Nakamura

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

Shin-ichiro Kubo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

Malcolm D Anthony

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

Robert H Edwards

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

language of work or name

English

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publication date

1 July 2004

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8 December 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

volume

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

page(s)

6715-6723

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein

12 May 2020

cites work

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12 December 2020

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

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12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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12 December 2020

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

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12 December 2020

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

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12 December 2020

alpha-Synuclein membrane interactions and lipid specificity

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12 December 2020

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

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12 December 2020

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

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12 December 2020

alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases

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12 December 2020

Activated Fyn phosphorylates alpha-synuclein at tyrosine residue 125.

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12 December 2020

Conformational properties of alpha-synuclein in its free and lipid-associated states

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12 December 2020

SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

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12 December 2020

SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.

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12 December 2020

Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

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12 December 2020

Lipid rafts and signal transduction

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12 December 2020

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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12 December 2020

alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

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12 December 2020

Lipid droplets: proteins floating on a pool of fat.

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12 December 2020

Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins.

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12 December 2020

Endocytosis without clathrin coats

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12 December 2020

Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form

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12 December 2020

Cholesterol depletion induces large scale domain segregation in living cell membranes

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12 December 2020

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

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12 December 2020

Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein

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12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

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12 December 2020

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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12 December 2020

Actin has a molecular scaffolding, not propulsive, role in presynaptic function.

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12 December 2020

A broken alpha -helix in folded alpha -Synuclein

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12 December 2020

Lipid binding inhibits alpha-synuclein fibril formation

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12 December 2020

Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability.

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12 December 2020

alpha-Synuclein locus triplication causes Parkinson's disease

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12 December 2020

Lipid rafts: elusive or illusive?

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12 December 2020

Yeast cells provide insight into alpha-synuclein biology and pathobiology

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12 December 2020

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

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12 December 2020

Nanoscale organization of multiple GPI-anchored proteins in living cell membranes.

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12 December 2020

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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12 December 2020

Caveolin, a protein component of caveolae membrane coats

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12 December 2020

Permeabilizing cells: some methods and applications for the study of intracellular processes

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12 December 2020

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

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12 December 2020

Adult rat brain synaptic vesicles. II. Lipid composition.

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12 December 2020

Fc epsilon RI-mediated recruitment of p53/56lyn to detergent-resistant membrane domains accompanies cellular signaling

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12 December 2020

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

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12 December 2020

Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

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12 December 2020

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

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12 December 2020

Identification of two distinct synucleins from human brain

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12 December 2020

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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12 December 2020

Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains

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12 December 2020

Construction of adenovirus vectors through Cre-lox recombination

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12 December 2020

Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Alpha-synuclein in Lewy bodies

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

Neuronal polarity: essential role of protein-lipid complexes in axonal sorting

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12 December 2020

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

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12 December 2020

Compartmentalization of phosphatidylinositol 4,5-bisphosphate in low-density membrane domains in the absence of caveolin

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12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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12 December 2020

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

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12 December 2020

Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains

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12 December 2020

Functions of lipid rafts in biological membranes

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12 December 2020

10.1523/JNEUROSCI.1594-04.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729723&resulttype=core&format=json

12 May 2020

1 reference