(Q5255119)

http://www.ebi.ac.uk/interpro/protein/P04075

TIM barrel

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P04075

Fructose-bisphosphate aldolase class-I active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

image

Fructose-1,6-bisphosphate aldolase 4ALD wpmp.png
698 × 837; 321 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

cytoskeletal protein binding

1 reference

9 May 2019

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Aldolase binding to actin-containing filaments. Formation of paracrystals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

fructose-bisphosphate aldolase activity

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 January 2018

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 January 2018

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 January 2018

Human skeletal-muscle aldolase: N-terminal sequence analysis of CNBr- and o-iodosobenzoic acid-cleavage fragments

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 reference

31 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 reference

31 October 2017

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 reference

9 May 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

identical protein binding

HDA

1 reference

9 May 2019

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

fructose-bisphosphate aldolase activity

HDA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

fructose-bisphosphate aldolase activity

5 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

31 October 2017

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

extracellular exosome

7 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

31 October 2017

Exosomes with immune modulatory features are present in human breast milk

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

platelet alpha granule lumen

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

31 October 2017

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

1 reference

31 October 2017

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

http://www.ebi.ac.uk/QuickGO/annotations?protein=P04075&geneProductId=UniProtKB:P04075

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

secretory granule lumen

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

tertiary granule lumen

1 reference

9 May 2019

ficolin-1-rich granule lumen

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Identification of sperm head proteins involved in zona pellucida binding

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Proteomic characterization of the human sperm nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

Defining the membrane proteome of NK cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

Exosomes with immune modulatory features are present in human breast milk

HDA

extracellular exosome

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

3 references

8 April 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

muscle cell cellular homeostasis

IEA

1 reference

9 May 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

actin filament organization

1 reference

9 May 2019

Aldolase binding to actin-containing filaments. Formation of paracrystals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

fructose metabolic process

1 reference

9 May 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

IMP

platelet degranulation

1 reference

9 May 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

ATP biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

Mode of interactions of human aldolase isozymes with cytoskeletons

IMP

regulation of cell shape

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

protein homotetramerization

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

striated muscle contraction

ISS

1 reference

9 May 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

IMP

neutrophil degranulation

1 reference

9 May 2019

binding of sperm to zona pellucida

1 reference

9 May 2019

Identification of sperm head proteins involved in zona pellucida binding

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

4 references

9 May 2019

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

fructose 1,6-bisphosphate metabolic process

IBA

3 references

9 May 2019

Mode of interactions of human aldolase isozymes with cytoskeletons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04075

Fructose-bisphosphate aldolase class-I active site

IBA

Gene Atlas image

PBB GE ALDOA 200966 x at fs.png
732 × 530; 12 KB

0 references

has part(s)

1 reference

stated in

InterPro Release 71.0