(Q53374378)

13 May 2018

title

Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes (English)

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

26 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

26 March 2024

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https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

26 March 2024

author name string

Sarah Drayton

1

1 reference

13 May 2018

Janice Rowe

2

1 reference

13 May 2018

Rebecca Jones

3

1 reference

13 May 2018

Radost Vatcheva

4

1 reference

13 May 2018

Darren Cuthbert-Heavens

5

1 reference

13 May 2018

John Marshall

6

1 reference

13 May 2018

Mike Fried

7

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13 May 2018

Gordon Peters

8

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13 May 2018

language of work or name

English

1 reference

National Center for Biotechnology Information

PubMed ID

14585357

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14585357

26 March 2024

publication date

1 October 2003

1 reference

13 May 2018

full work available at URL

http://www.cell.com/article/S1535610803002423/pdf

file format

Portable Document Format

online access status

open access

1 reference

PubMed ID

14585357

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585357

https://api.elsevier.com/content/article/PII:S1535610803002423?httpAccept=text/xml

26 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

https://api.elsevier.com/content/article/PII:S1535610803002423?httpAccept=text/plain

26 March 2024

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

26 March 2024

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13 May 2018

volume

4

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13 May 2018

issue

4

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13 May 2018

page(s)

301-310

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13 May 2018

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

1 reference

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7 January 2021

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest

1 reference

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7 January 2021

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Immortalisation and transformation revisited

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7 January 2021

An optimized, fully automated system for fast and accurate identification of chromosomal rearrangements by multiplex-FISH (M-FISH).

1 reference

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

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7 January 2021

Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Creation of human tumour cells with defined genetic elements

1 reference

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7 January 2021

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Identification of CDK4 as a target of c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Negative regulation of the mammalian UV response by Myc through association with Miz-1

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Expression of mouse telomerase catalytic subunit in embryos and adult tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

1 reference

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7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Suppression of tumor growth by senescence in virally transformed human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

The INK4A/ARF locus and its two gene products

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

The INK4a/ARF network in tumour suppression

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7 January 2021

Cellular senescence: mitotic clock or culture shock?

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Activated v-myc and v-ras oncogenes do not transform normal human lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

The tumor-suppressive functions of the human INK4A locus

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Historical claims and current interpretations of replicative aging

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900242-3

7 January 2021

Tumorigenic transformation of spontaneously immortalized fibroblasts from patients with a familial cancer syndrome

2

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts

26 March 2024

53

1 reference

https://api.crossref.org/works/10.1016/S1535-6108(03)00242-3

26 March 2024

Identifiers

1 reference

13 May 2018

PubMed ID

14585357

1 reference

13 May 2018