(Q53581072)

15 May 2018

title

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. (English)

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15 May 2018

main subject

ataxia telangiectasia

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Benjamin P C Chen

1

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15 May 2018

Naoya Uematsu

2

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15 May 2018

Junya Kobayashi

3

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15 May 2018

Yaniv Lerenthal

4

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15 May 2018

Andrea Krempler

5

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15 May 2018

Hirohiko Yajima

6

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15 May 2018

Markus Löbrich

7

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15 May 2018

Yosef Shiloh

8

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15 May 2018

David J Chen

9

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15 May 2018

language of work or name

English

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publication date

21 December 2006

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15 May 2018

Journal of Biological Chemistry

published in

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15 May 2018

volume

282

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15 May 2018

issue

9

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15 May 2018

page(s)

6582-6587

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15 May 2018

Chromosomal stability and the DNA double-stranded break connection

cites work

1 reference

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The cellular response to general and programmed DNA double strand breaks

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DNA double-strand break repair: all's well that ends well

21 January 2018

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Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining

21 January 2018

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Role of DNA-PK in the cellular response to DNA double-strand breaks

21 January 2018

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Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks.

21 January 2018

1 reference

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The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

Substrate specificities and identification of putative substrates of ATM kinase family members

21 January 2018

1 reference

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SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA-damage-response proteins

21 January 2018

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21 January 2018

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Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

21 January 2018

1 reference

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The ATM-mediated DNA-damage response: taking shape.

21 January 2018

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A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity

21 January 2018

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A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

21 January 2018

1 reference

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The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner

21 January 2018

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Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells

21 January 2018

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

21 January 2018

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Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

21 January 2018

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Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

21 January 2018

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Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM.

21 January 2018

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21 January 2018

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DNA-PK autophosphorylation facilitates Artemis endonuclease activity

21 January 2018

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BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 January 2018

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The BRCT Domain Is a Phospho-Protein Binding Domain

21 January 2018

1 reference

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Mdt1, a novel Rad53 FHA1 domain-interacting protein, modulates DNA damage tolerance and G(2)/M cell cycle progression in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

DNA-PKcs function regulated specifically by protein phosphatase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611605200

21 January 2018

Identifiers

DOI

10.1074/JBC.M611605200

1 reference

15 May 2018

PubMed ID

17189255

1 reference

15 May 2018