(Q55069557)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Christopher T. Turner

3

1 reference

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29 March 2020

Haishan Zeng

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Dale R. Cameron

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

author name string

Yue Shen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Sheetal A Raithatha

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Zhenguo Wu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Valerio Russo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Cameron Oram

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Sho Hiroyasu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Layla Nabai

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Hongyan Zhao

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Tatjana Bozin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Kathryn Westendorf

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Irina Kopko

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Rachel Huang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Steve Arns

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Jason Tan

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Anthony Boey

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Richard Liggins

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

James Jaquith

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

Anthony Papp

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

David J Granville

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

publication date

30 May 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

Experimental and Molecular Medicine

29 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

page(s)

1-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

29 March 2020

copyright license

start time

1 May 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5976625/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s12276-018-0095-0

0 references

cites work

Decorin reduces hypertrophic scarring through inhibition of the TGF-β1/Smad signaling pathway in a rat osteomyelitis model

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Granzyme B mediates both direct and indirect cleavage of extracellular matrix in skin after chronic low-dose ultraviolet light irradiation

18 June 2018

1 reference

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Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing

18 June 2018

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Smoking, chronic wound healing, and implications for evidence-based practice

18 June 2018

1 reference

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Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability

18 June 2018

1 reference

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Perforin and granzyme B have separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout mice

18 June 2018

1 reference

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Granzyme B degrades extracellular matrix and contributes to delayed wound closure in apolipoprotein E knockout mice

18 June 2018

1 reference

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Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

18 June 2018

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Granzyme B in injury, inflammation, and repair

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Granzyme B cleaves decorin, biglycan and soluble betaglycan, releasing active transforming growth factor-β1

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Epidemiology and impact of scarring after burn injury: a systematic review of the literature

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

US skin disease assessment: ulcer and wound care

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar

18 June 2018

1 reference

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Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice.

18 June 2018

1 reference

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Benefit-risk assessment of becaplermin in the treatment of diabetic foot ulcers

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Perforin-independent extracellular granzyme B activity contributes to abdominal aortic aneurysm

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Updated biological roles for matrix metalloproteinases and new "intracellular" substrates revealed by degradomics

18 June 2018

1 reference

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Progress in matrix metalloproteinase research

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

The diabetic foot: grand overview, epidemiology and pathogenesis.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

18 June 2018

Impaired wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

The major human and mouse granzymes are structurally and functionally divergent

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Extracellular matrix remodeling by human granzyme B via cleavage of vitronectin, fibronectin, and laminin.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

A specialized wound-healing center concept: importance of a multidisciplinary department structure and surgical treatment facilities in the treatment of chronic wounds

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

The role of decorin in collagen fibrillogenesis and skin homeostasis

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

18 June 2018

Cutaneous wound healing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

The pathogenesis of type II diabetes mellitus. A polygenic disease

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

17 The kinetics of reversible tight-binding inhibition

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Current concepts related to hypertrophic scarring in burn injuries.

18 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Targeted Antiscarring Therapy for Tissue Injuries

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Granzyme B cleavage of fibronectin disrupts endothelial cell adhesion, migration and capillary tube formation.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Reduced decorin, fibromodulin, and transforming growth factor-β3 in deep dermis leads to hypertrophic scarring.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Wound closure and metabolic parameter variability in a db/db mouse model for diabetic ulcers

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

A role for decorin in cutaneous wound healing and angiogenesis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Determination of accurate KI values for tight-binding enzyme inhibitors: an in silico study of experimental error and assay design.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5976625

Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors

13 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Fibronectin fragmentation is a feature of periodontal disease sites and diabetic foot and leg wounds and modifies cell behavior

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Delayed appearance of decorin in healing burn scars

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Python for Scientific Computing

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

The NumPy Array: A Structure for Efficient Numerical Computation

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

In vivo video rate multiphoton microscopy imaging of human skin

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Level of fibronectin mRNA is markedly increased in human chronic wounds

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

Venous ulcer fibroblasts compared with normal fibroblasts show differences in collagen but not fibronectin production under both normal and hypoxic conditions

1 reference

https://api.crossref.org/works/10.1038%2FS12276-018-0095-0

7 January 2021

10.1038/S12276-018-0095-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29849046%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference