(Q58854284)

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New PCR Primers for the Screening of NRPS and PKS-I Systems in Actinomycetes: Detection and Distribution of These Biosynthetic Gene Sequences in Major Taxonomic Groups

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15614464%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

New PCR primers for the screening of NRPS and PKS-I systems in actinomycetes: detection and distribution of these biosynthetic gene sequences in major taxonomic groups (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15614464%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Angel Ayuso-Sacido

1

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Europe PubMed Central

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6 January 2020

2

1 reference

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6 January 2020

publication date

21 December 2004

1 reference

Europe PubMed Central

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6 January 2020

Microbial Ecology

1 reference

Europe PubMed Central

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6 January 2020

49

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6 January 2020

1

1 reference

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6 January 2020

10-24

1 reference

Europe PubMed Central

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6 January 2020

https://scigraph.springernature.com/pub.10.1007/s00248-004-0249-6

0 references

Identification and cloning of a gene locus encoding peptide synthetase of Pseudomonas fluorescens by two sets of PCR primers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryptosporidium parvum: the first protist known to encode a putative polyketide synthase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second type-I PKS gene cluster isolated from Streptomyces hygroscopicus ATCC 29253, a rapamycin-producing strain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How do peptide synthetases generate structural diversity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cephamycin biosynthetic genes pcbAB, encoding a large multidomain peptide synthetase, and pcbC of Nocardia lactamdurans are clustered together in an organization different from the same genes in Acremonium chrysogenum and Penicillium chrysogenum

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The detection of diverse aminoglycoside phosphotransferases within natural populations of actinomycetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new cytotoxic epothilone from modified polyketide synthases heterologously expressed in Myxococcus xanthus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of D-alanyl-lipoteichoic acid: cloning, nucleotide sequence, and expression of the Lactobacillus casei gene for the D-alanine-activating enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and sequence analysis of the putative rifamycin polyketide synthase gene cluster from Amycolatopsis mediterranei

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and analysis of a peptide synthetase gene of the balhimycin producer Amycolatopsis mediterranei DSM5908 and development of a gene disruption/replacement system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heterologous expression in Escherichia coli of the first module of the nonribosomal peptide synthetase for chloroeremomycin, a vancomycin-type glycopeptide antibiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and utility of oligonucleotide gene probes for fungal polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic architecture of the polyketide synthases for methymycin and pikromycin series macrolides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketosynthase domain probes identify two subclasses of fungal polyketide synthase genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Origin of starter units for erythromycin biosynthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A general approach for identifying and cloning peptide synthetase genes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonribosomal biosynthesis of vancomycin-type antibiotics: a heptapeptide backbone and eight peptide synthetase modules

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance and specificity of polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple peptide synthetase gene clusters in Actinomycetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of the actinomycin synthetase gene cluster from Streptomyces chrysomallus and functional heterologous expression of the gene encoding actinomycin synthetase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein templates for the biosynthesis of peptide antibiotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of Eubacterial 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductases from Natural Populations of Actinomycetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modular structure of genes encoding multifunctional peptide synthetases required for non-ribosomal peptide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Streptogramin B biosynthesis in Streptomyces pristinaespiralis and Streptomyces virginiae: molecular characterization of the last structural peptide synthetase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in the stability of DNA-peptide nucleic acid (PNA) single-base mismatched duplexes: real-time hybridization during affinity electrophoresis in PNA-containing gels

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of D-alanine into lipoteichoic acid and wall teichoic acid in Bacillus subtilis. Identification of genes and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ways of assembling complex natural products on modular nonribosomal peptide synthetases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic diversity in myxobacteria: identification of the myxalamid and the stigmatellin biosynthetic gene cluster of Stigmatella aurantiaca Sg a15 and a combined polyketide-(poly)peptide gene cluster from the epothilone producing strain Sorangium

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonribosomal peptide synthetase genes occur in most cyanobacterial genera as evidenced by their distribution in axenic strains of the PCC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15614464

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00248-004-0249-6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15614464%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15614464%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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