(Q59803350)

12 December 2020

Glucosinolates and their breakdown products in food and food plants

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12 December 2020

Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin

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12 December 2020

Cyclooxygenase-2: regulation and relevance in inflammation

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12 December 2020

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

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12 December 2020

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

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12 December 2020

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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12 December 2020

Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells.

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12 December 2020

Signal transduction. FasL binds preassembled Fas

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12 December 2020

Adverse drug reactions: definitions, diagnosis, and management

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12 December 2020

Surfing the p53 network

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12 December 2020

Inhibition of carcinogenesis by isothiocyanates

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12 December 2020

Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates

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12 December 2020

Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans

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12 December 2020

Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

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12 December 2020

Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli

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12 December 2020

Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis

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12 December 2020

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

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12 December 2020

Brassica, biotransformation and cancer risk: genetic polymorphisms alter the preventive effects of cruciferous vegetables

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12 December 2020

The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells.

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12 December 2020

Selected isothiocyanates rapidly induce growth inhibition of cancer cells.

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12 December 2020

Hydrolysis of glucosinolates to isothiocyanates after ingestion of raw or microwaved cabbage by human volunteers.

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12 December 2020

Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells

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12 December 2020

Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells.

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12 December 2020

Hypoxia induces HIF-1Œ± and VEGF expression in chondrosarcoma cells and chondrocytes

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12 December 2020

Bone morphogenetic proteins

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12 December 2020

Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells

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12 December 2020

p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.

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12 December 2020

NF-kappaB activation in melanoma

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12 December 2020

Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane

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12 December 2020

D,L-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1.

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12 December 2020

Matrix metalloproteinases (MMPs): chemical-biological functions and (Q)SARs

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12 December 2020

Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

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12 December 2020

Quantitative combination effects between sulforaphane and 3,3'-diindolylmethane on proliferation of human colon cancer cells in vitro.

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12 December 2020

The emerging roles of forkhead box (Fox) proteins in cancer

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12 December 2020

Cellular and molecular mechanisms of fibrosis

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12 December 2020

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

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12 December 2020

Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism

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12 December 2020

Consumption of raw cruciferous vegetables is inversely associated with bladder cancer risk.

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12 December 2020

Kinetics of histone H2AX phosphorylation and Chk2 activation in A549 cells treated with topotecan and mitoxantrone in relation to the cell cycle phase

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12 December 2020

Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis

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12 December 2020

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

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12 December 2020

Cancer is a preventable disease that requires major lifestyle changes

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12 December 2020

Glucosinolates in Brassica vegetables: the influence of the food supply chain on intake, bioavailability and human health.

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12 December 2020

Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-kappaB-DNA-binding activity in human bladder T24 cells.

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12 December 2020

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.

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12 December 2020

CD44v6 dependence of premetastatic niche preparation by exosomes

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12 December 2020

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

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12 December 2020

NF-kappaB signaling pathway, inflammation and colorectal cancer.

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12 December 2020

Dietary glucosinolate intake, polymorphisms in selected biotransformation enzymes, and risk of prostate cancer

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12 December 2020

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway

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12 December 2020

Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo

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12 December 2020

p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells

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12 December 2020

Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells

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12 December 2020

Inhibiting NF-κB activation by small molecules as a therapeutic strategy

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12 December 2020

Synergistic activity of sorafenib and sulforaphane abolishes pancreatic cancer stem cell characteristics

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12 December 2020

Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells

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12 December 2020

BITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-induced Apoptosis

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12 December 2020

Phenethyl Isothiocyanate Inhibited Tumor Migration and Invasion via Suppressing Multiple Signal Transduction Pathways in Human Colon Cancer HT29 Cells

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12 December 2020

Allyl-, butyl- and phenylethyl-isothiocyanate activate Nrf2 in cultured fibroblasts

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12 December 2020

Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway

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12 December 2020

Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human oste

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12 December 2020

Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.

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12 December 2020

Phenethyl isothiocyanate promotes immune responses in normal BALB/c mice, inhibits murine leukemia WEHI-3 cells, and stimulates immunomodulations in vivo

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12 December 2020

Combination treatment with 5-fluorouracil and isothiocyanates shows an antagonistic effect in Chinese hamster fibroblast cells line-V79.

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12 December 2020

Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): evidence for TRPA1-independent effects

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12 December 2020

Autophagy: renovation of cells and tissues

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12 December 2020

Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells

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12 December 2020

Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging

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12 December 2020

Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer cultures

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12 December 2020

Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models

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12 December 2020

Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model

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12 December 2020

Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells

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12 December 2020

Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)

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12 December 2020

Sulforaphane inhibits growth of phenotypically different breast cancer cells

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12 December 2020

Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation.

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12 December 2020

Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo.

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12 December 2020

HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates

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12 December 2020

Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation.

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12 December 2020

Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells

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12 December 2020

RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis.

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12 December 2020

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1

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12 December 2020

Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.

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12 December 2020

Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities

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12 December 2020

Sulforaphane inhibits phorbol ester-stimulated IKK-NF-κB signaling and COX-2 expression in human mammary epithelial cells by targeting NF-κB activating kinase and ERK.

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12 December 2020

Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases

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12 December 2020

Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway.

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12 December 2020

Effect of redox modulating NRF2 activators on chronic kidney disease

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12 December 2020

Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells

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12 December 2020

Potential mechanisms of benzyl isothiocyanate suppression of invasion and angiogenesis by the U87MG human glioma cell line

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12 December 2020

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

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12 December 2020

SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells

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12 December 2020

Oxidized low-density lipoprotein is associated with advanced-stage prostate cancer.

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12 December 2020

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

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12 December 2020

Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210

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12 December 2020

Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism

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12 December 2020

Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression.

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12 December 2020

Benzyl isothiocyanate alters the gene expression with cell cycle regulation and cell death in human brain glioblastoma GBM 8401 cells

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12 December 2020

Functional analysis of three BrMYB28 transcription factors controlling the biosynthesis of glucosinolates in Brassica rapa

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12 December 2020

Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194.

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12 December 2020

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

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12 December 2020

Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.

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12 December 2020

Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells

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12 December 2020

Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways.

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12 December 2020

The cancer stem-cell signaling network and resistance to therapy

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12 December 2020

Benzyl Isothiocyanate (BITC) Induces Reactive Oxygen Species-dependent Repression of STAT3 Protein by Down-regulation of Specificity Proteins in Pancreatic Cancer

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12 December 2020

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study

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12 December 2020

Phenethyl isothiocyanate suppresses the metastasis of ovarian cancer associated with the inhibition of CRM1-mediated nuclear export and mTOR-STAT3 pathway

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12 December 2020

Sulforaphane induces differential modulation of mitochondrial biogenesis and dynamics in normal cells and tumor cells.

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12 December 2020

Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles

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12 December 2020

Benzyl Isothiocyanate potentiates p53 signaling and antitumor effects against breast cancer through activation of p53-LKB1 and p73-LKB1 axes

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12 December 2020

Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation.

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12 December 2020

Benzyl-isothiocyanate Induces Apoptosis and Inhibits Migration and Invasion of Hepatocellular Carcinoma Cells in vitro

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12 December 2020

Fatty Acid Synthesis Intermediates Represent Novel Noninvasive Biomarkers of Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate

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12 December 2020

Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.

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12 December 2020

E-Cadherin/β-Catenin Complex: A Target for Anticancer and Antimetastasis Plants/Plant-derived Compounds

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12 December 2020

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

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12 December 2020

A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells

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12 December 2020

Breast cancer oral anti-cancer medication adherence: a systematic review of psychosocial motivators and barriers

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12 December 2020

Two likely targets for the anti-cancer effect of indole derivatives from cruciferous vegetables: PI3K/Akt/mTOR signalling pathway and the aryl hydrocarbon receptor

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12 December 2020

Brassica-Derived Plant Bioactives as Modulators of Chemopreventive and Inflammatory Signaling Pathways

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12 December 2020

Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer

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12 December 2020

Transcription factors NRF2 and HSF1 have opposing functions in autophagy

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12 December 2020

Understanding of MYB Transcription Factors Involved in Glucosinolate Biosynthesis in Brassicaceae.

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12 December 2020

Prevention of breast cancer-induced osteolytic bone resorption by benzyl isothiocyanate.

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12 December 2020

Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation

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12 December 2020

Expression profiles of BrMYB transcription factors related to glucosinolate biosynthesis and stress response in eight subspecies of Brassica rapa

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12 December 2020

Epimedium koreanum Nakai inhibits PMA-induced cancer cell migration and invasion by modulating NF-κB/MMP-9 signaling in monomorphic malignant human glioma cells.

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12 December 2020

Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells.

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12 December 2020

Correction to: Dietary intake of soy and cruciferous vegetables and treatment-related symptoms in Chinese-American and non-Hispanic White breast cancer survivors.

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12 December 2020

Sulforaphane metabolites cause apoptosis via microtubule disruption in cancer.

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12 December 2020

TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate-induced growth inhibition in pancreatic cancer cells.

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12 December 2020

Anti-fibrotic potential of a Matthiola arabica isothiocyanates rich fraction: impact on oxidative stress, inflammatory and fibrosis markers.

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12 December 2020

Lung Cancer Chemopreventive Activity of Patulin Isolated from Penicillium vulpinum

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12 December 2020

Inhibition of Glycolysis in Prostate Cancer Chemoprevention by Phenethyl Isothiocyanate.

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12 December 2020

HDAC5-LSD1 axis regulates antineoplastic effect of natural HDAC inhibitor sulforaphane in human breast cancer cells.

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12 December 2020

Glucosinolate and isothiocyanate intakes are inversely associated with breast cancer risk: a case-control study in China.

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12 December 2020

Allyl isothiocyanate reduces liver fibrosis by regulating Kupffer cell activation in rats.

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12 December 2020

Extraction, profiling and bioactivity analysis of volatile glucosinolates present in oil extract of Brassica juncea var. raya.

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12 December 2020

Usual Cruciferous Vegetable Consumption and Ovarian Cancer: A Case-Control Study

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12 December 2020

Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs

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12 December 2020

Benzyl isothiocyanate inhibits human brain glioblastoma multiforme GBM 8401 cell xenograft tumor in nude mice in vivo

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12 December 2020

Cruciferous Vegetables, Isothiocyanates, and Bladder Cancer Prevention

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12 December 2020

Sulforaphane absorption and histone deacetylase activity following single dosing of broccoli sprout supplement in normal dogs

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12 December 2020

Methyl-β-cyclodextrin potentiates the BITC-induced anti-cancer effect through modulation of the Akt phosphorylation in human colorectal cancer cells

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12 December 2020

Broccoli consumption affects the human gastrointestinal microbiota

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12 December 2020