(Q21032535)

Chemotherapy for falciparum malaria: the armoury, the problems and the prospects

PubMed

volume

4

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issue

6

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page(s)

783-797

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cites work

1 reference

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

21 January 2018

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First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

21 January 2018

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21 January 2018

A vaccine for malaria.

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Organometallic anticancer compounds

21 January 2018

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Metal-based antitumour drugs in the post genomic era.

21 January 2018

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Antimalarial activity of ferrocenyl chalcones

21 January 2018

1 reference

Synthesis of novel ferrocenyl sugars and their antimalarial activities

21 January 2018

1 reference

Probing structure/affinity relationships for the Plasmodium falciparum hexose transporter with glucose derivatives

21 January 2018

1 reference

Synthesis, structure, and biological activity of ferrocenyl carbohydrate conjugates

21 January 2018

1 reference

In vitro antimalarial activity of chalcones and their derivatives

21 January 2018

1 reference

Licochalcone A, a new antimalarial agent, inhibits in vitro growth of the human malaria parasite Plasmodium falciparum and protects mice from P. yoelii infection

21 January 2018

1 reference

Antiplasmodial activity of ferrocenyl chalcones: investigations into the role of ferrocene

21 January 2018

1 reference

New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity

21 January 2018

1 reference

New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity--Part II.

21 January 2018

1 reference

Synthesis and chloroquine-enhancing activity of Na-deacetyl-ferrocenoyl-strychnobrasiline

21 January 2018

1 reference

Novel ferrocenic artemisinin derivatives: synthesis, in vitro antimalarial activity and affinity of binding with ferroprotoporphyrin IX.

21 January 2018

1 reference

Synthetic ferrocenic mefloquine and quinine analoguesas potential antimalarial agents.

21 January 2018

1 reference

Synthesis and in vitro activities of ferrocenic aminohydroxynaphthoquinones against Toxoplasma gondii and Plasmodium falciparum

21 January 2018

1 reference

A plastid organelle as a drug target in apicomplexan parasites.

21 January 2018

1 reference

Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplast

21 January 2018

1 reference

Quinolone-based drugs against Toxoplasma gondii and Plasmodium spp.

21 January 2018

1 reference

Growth inhibition of Toxoplasma gondii and Plasmodium falciparum by nanomolar concentrations of 1-hydroxy-2-dodecyl-4(1H)quinolone, a high-affinity inhibitor of alternative (type II) NADH dehydrogenases

21 January 2018

1 reference

Antimalarial quinolones: synthesis, potency, and mechanistic studies

21 January 2018

1 reference

Enhancement of the antimalarial activity of ciprofloxacin using a double prodrug/bioorganometallic approach

21 January 2018

1 reference

The effects of anti-bacterials on the malaria parasite Plasmodium falciparum.

21 January 2018

1 reference

Structure-activity relationships for antiplasmodial activity among 7-substituted 4-aminoquinolines.

21 January 2018

1 reference

Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities.

21 January 2018

1 reference

Probing the role of the covalent linkage of ferrocene into a chloroquine template

21 January 2018

1 reference

The antimalarial ferroquine: from bench to clinic

21 January 2018

1 reference

Synthesis and antimalarial activity in vitro and in vivo of a new ferrocene-chloroquine analogue.

21 January 2018

1 reference

Ex vivo drug susceptibility of ferroquine against chloroquine-resistant isolates of Plasmodium falciparum and P. vivax

21 January 2018

1 reference

Plasmodium vivax susceptibility to ferroquine

21 January 2018

1 reference

Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection

21 January 2018

1 reference

The antimalarial ferroquine: role of the metal and intramolecular hydrogen bond in activity and resistance

21 January 2018

1 reference

Chloroquine transport via the malaria parasite's chloroquine resistance transporter

21 January 2018

1 reference

Insights into the mechanism of action of ferroquine. Relationship between physicochemical properties and antiplasmodial activity.

21 January 2018

1 reference

Ferroquine, an ingenious antimalarial drug: thoughts on the mechanism of action.

21 January 2018

1 reference

Investigation of the redox behavior of ferroquine, a new antimalarial

21 January 2018

1 reference

Hydroxychloroquine is much less active than chloroquine against chloroquine-resistant Plasmodium falciparum, in agreement with its physicochemical properties

21 January 2018

1 reference

In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing N-desethylchloroquine formation.

21 January 2018

1 reference

In vitro metabolism of ferroquine (SSR97193) in animal and human hepatic models and antimalarial activity of major metabolites on Plasmodium falciparum.

21 January 2018

1 reference

Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker

21 January 2018

1 reference

Glutathione reductase-catalyzed cascade of redox reactions to bioactivate potent antimalarial 1,4-naphthoquinones--a new strategy to combat malarial parasites

21 January 2018

1 reference

Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides

21 January 2018

1 reference

Design, synthesis, and antimalarial activity of structural chimeras of thiosemicarbazone and ferroquine analogues

21 January 2018

1 reference

Selection of a trioxaquine as an antimalarial drug candidate

21 January 2018

1 reference

Trioxaferroquines as new hybrid antimalarial drugs.

21 January 2018

1 reference

Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo[1,2-a]quinoxalines as antileishmanial agents

21 January 2018

1 reference

7 January 2021

Correlation of antimalarial activity of artemisinin derivatives with binding affinity with ferroprotoporphyrin IX

1 reference

7 January 2021

In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes

1 reference

7 January 2021

In vitro antimalarial activity of a new organometallic analog, ferrocene-chloroquine

1 reference

7 January 2021