(Q21089590)

2

Della

Friend

1 reference

4 August 2022

James Jaffe

3

James

Jaffe

1 reference

4 August 2022

Mesfin Gewe

4

Mesfin

Gewe

1 reference

4 August 2022

Margaret A Holmes

5

Margaret A

Holmes

1 reference

4 August 2022

H Benjamin Larman

6

H Benjamin

Larman

1 reference

4 August 2022

Andrew Stuart

7

Andrew

Stuart

1 reference

4 August 2022

Kevin Larimore

8

Kevin

Larimore

1 reference

4 August 2022

Philip D Greenberg

9

Philip D

Greenberg

1 reference

4 August 2022

Roland K Strong

12

Roland K

Creative Commons Attribution 4.0 International

Strong

1 reference

4 August 2022

language of work or name

English

0 references

publication date

September 2014

0 references

published in

PLOS Pathogens

0 references

volume

10

0 references

issue

9

0 references

page(s)

e1004403

0 references

copyright license

start time

25 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

19 March 2017

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Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies

19 March 2017

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19 March 2017

The Protein Data Bank

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Kabat Database and its applications: 30 years after the first variability plot

19 March 2017

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Antibodies in HIV-1 vaccine development and therapy

19 March 2017

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A global approach to HIV-1 vaccine development

19 March 2017

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HIV-1 antibodies from infection and vaccination: insights for guiding vaccine design

19 March 2017

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Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

19 March 2017

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

19 March 2017

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Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody

19 March 2017

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Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

19 March 2017

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Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

19 March 2017

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Structural and genetic basis for development of broadly neutralizing influenza antibodies

19 March 2017

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

19 March 2017

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

19 March 2017

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Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

19 March 2017

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

19 March 2017

1 reference

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Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

19 March 2017

1 reference

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Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus

19 March 2017

1 reference

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Germline antibody recognition of distinct carbohydrate epitopes

19 March 2017

1 reference

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A comparative analysis of the immunological evolution of antibody 28B4

19 March 2017

1 reference

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Structural insights into the evolution of an antibody combining site

19 March 2017

1 reference

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Phasercrystallographic software

19 March 2017

1 reference

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Coot: model-building tools for molecular graphics

19 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

19 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

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A graphical user interface to the CCP4 program suite

19 March 2017

1 reference

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The finer things in X-ray diffraction data collection

19 March 2017

2 references

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19 March 2017

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Shape complementarity at protein/protein interfaces

12 September 2017

1 reference

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Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41

19 March 2017

1 reference

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Multi-constraint computational design suggests that native sequences of germline antibody H3 loops are nearly optimal for conformational flexibility

19 March 2017

1 reference

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Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10

19 March 2017

1 reference

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Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10

12 September 2017

1 reference

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Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

12 September 2017

1 reference

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Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency

12 September 2017

1 reference

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HIV vaccine design: the neutralizing antibody conundrum

12 September 2017

1 reference

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Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Conformational selection or induced fit? 50 years of debate resolved

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Autoantigen discovery with a synthetic human peptidome

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Comparison of antibody repertoires produced by HIV-1 infection, other chronic and acute infections, and systemic autoimmune disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Antagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Scaffolding to build a rational vaccine design strategy

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Role of HIV membrane in neutralization by two broadly neutralizing antibodies

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

iHMMune-align: hidden Markov model-based alignment and identification of germline genes in rearranged immunoglobulin gene sequences

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Antibody responses elicited in macaques immunized with human immunodeficiency virus type 1 (HIV-1) SF162-derived gp140 envelope immunogens: comparison with those elicited during homologous simian/human immunodeficiency virus SHIVSF162P4 and heterolo

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

IMGT/V-QUEST, an integrated software program for immunoglobulin and T cell receptor V-J and V-D-J rearrangement analysis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Antibodies, viruses and vaccines

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Kinetic and affinity limits on antibodies produced during immune responses

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Three-Dimensional Structure of Immunoglobulins

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Processing of X-ray diffraction data collected in oscillation mode

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

HotPatch: a statistical approach to finding biologically relevant features on protein surfaces

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Distinct biological and serological properties of human immunodeficiency viruses from the brain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Shaping of human germline IgH repertoires revealed by deep sequencing

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

Structural plasticity and the evolution of antibody affinity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

A Theory of the Structure and Process of Formation of Antibodies*

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

HIV-1 subtype A envelope variants from early in infection have variable sensitivity to neutralization and to inhibitors of viral entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

Characterization of the human Ig heavy chain antigen binding complementarity determining region 3 using a newly developed software algorithm, JOINSOLVER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004403

Progress in HIV-1 vaccine development

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177983

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

29 November 2018

1 reference

12 December 2020

Improving biosensor analysis

1 reference

12 December 2020

Preferred CDRH3 lengths for antibodies with defined specificities

1 reference

12 December 2020

Differential epitope positioning within the germline antibody paratope enhances promiscuity in the primary immune response

1 reference

12 December 2020

Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells

1 reference

12 December 2020

Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design

1 reference

12 December 2020

Structural differences among monoclonal antibodies with distinct fine specificities and kinetic properties

1 reference

12 December 2020