Wikidata

(Q21107535)

English

Mitogen-activated protein kinase kinase 6

mammalian protein found in Homo sapiens

  • SAPK kinase 3
  • SAPKK3
  • SAPKK-3
  • MEK 6
  • protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)
  • MAPKK 6
  • stress-activated protein kinase kinase 3
  • MAPK/ERK kinase 6
  • dual specificity mitogen-activated protein kinase kinase 6
  • MAP2K6
In more languages

Statements

molecular function
protein binding
determination method
IPI
5 references
retrieved
8 April 2019
stated in
Protein kinase R (PKR) interacts with and activates mitogen-activated protein kinase kinase 6 (MKK6) in response to double-stranded RNA stimulation
GOA
curator
UniProt
UniProt protein ID
P52564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IPI
retrieved
8 April 2019
stated in
C-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB)
GOA
curator
UniProt
UniProt protein ID
P52564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IPI
retrieved
8 April 2019
stated in
MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IPI
MAP kinase kinase activity
determination method
IBA
IDA
IEA
TAS
6 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
TAS
retrieved
8 April 2019
stated in
Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IEA
retrieved
8 April 2019
stated in
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
GOA
curator
UniProt
UniProt protein ID
P52564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IDA
retrieved
8 April 2019
stated in
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
GOA
curator
UniProt
UniProt protein ID
P52564
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P52564
determination method
IBA
cell component
biological process

Identifiers

MeSH descriptor ID
D048669
subject named as
MAP Kinase Kinase 6
0 references
 
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