Wikidata

(Q21109157)

English

Polo like kinase 4

mammalian protein found in Homo sapiens

  • serine/threonine-protein kinase Sak
  • serine/threonine-protein kinase PLK4
  • Snk akin kinase
  • serine/threonine-protein kinase 18
  • PLK4
  • PLK-4
  • Polo-like kinase 4
In more languages

Statements

molecular function
protein serine/threonine kinase activity
determination method
IDA
ISS
IEA
TAS
7 references
retrieved
10 September 2018
stated in
Sak kinase gene structure and transcriptional regulation
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
TAS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
ISS
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
10 September 2018
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
10 September 2018
stated in
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Asterless is a scaffold for the onset of centriole assembly
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Plk4 is required for cytokinesis and maintenance of chromosomal stability
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Asterless is a scaffold for the onset of centriole assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
STIL binding to Polo-box 3 of PLK4 regulates centriole duplication
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
retrieved
8 April 2019
stated in
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IPI
protein serine/threonine kinase activity
determination method
IBA
IDA
IEA
ISS
TAS
8 references
retrieved
8 April 2019
stated in
Sak kinase gene structure and transcriptional regulation
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
8 April 2019
stated in
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IBA
cell component
centriole
determination method
IDA
IEA
6 references
retrieved
10 September 2018
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
10 September 2018
stated in
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
10 September 2018
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
10 September 2018
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
10 September 2018
stated in
The Polo kinase Plk4 functions in centriole duplication
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=O00444&geneProductId=UniProtKB:O00444
determination method
IDA
centriole
determination method
IBA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IEA
retrieved
8 April 2019
stated in
The Polo kinase Plk4 functions in centriole duplication
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
Plk4-induced centriole biogenesis in human cells
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation
GOA
curator
UniProt
UniProt protein ID
O00444
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00444
determination method
IBA
biological process

Identifiers

 
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