(Q21109162)

Apoptotic protease-activating factor 1

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

WD40-repeat-containing domain superfamily

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

Death-like domain superfamily

1 reference

Apoptotic Protease-Activating Factor 1, CARD domain, protein family

1 reference

CARD domain, protein family

1 reference

NB-ARC domain, protein family

1 reference

WD40 repeat, protein family

1 reference

WD40 repeat, conserved site, protein family

1 reference

G-protein beta WD-40 repeat, protein family

1 reference

heat shock protein binding

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

15 references

8 April 2019

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Rsk-mediated phosphorylation and 14-3-3ɛ binding of Apaf-1 suppresses cytochrome c-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Structure of an apoptosome-procaspase-9 CARD complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

A mutational epitope for cytochrome C binding to the apoptosis protease activation factor-1

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

identical protein binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

cysteine-type endopeptidase activator activity involved in apoptotic process

4 references

8 April 2019

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Analysis of APAF-1 expression in human cutaneous melanoma progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

31 October 2017

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

4 references

31 October 2017

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

31 October 2017

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

secretory granule lumen

1 reference

8 April 2019

ficolin-1-rich granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

protein-containing complex

IBA

1 reference

8 April 2019

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

5 references

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

Large-scale proteomics and phosphoproteomics of urinary exosomes

IBA

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

cellular response to transforming growth factor beta stimulus

HDA

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

neuron apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

response to G1 DNA damage checkpoint signaling

1 reference

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

positive regulation of apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

glial cell apoptotic process

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O14727&geneProductId=UniProtKB:O14727

nervous system development

1 reference

8 April 2019

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

multicellular organism development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

cardiac muscle cell apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

intrinsic apoptotic signaling pathway

1 reference

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

positive regulation of apoptotic process

1 reference

8 April 2019

No death without life: vital functions of apoptotic effectors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

forebrain development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

regulation of apoptotic DNA fragmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

protein homooligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

neutrophil degranulation

1 reference

8 April 2019

negative regulation of G0 to G1 transition

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

IBA

IDA

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14727

1 reference

G-protein beta WD-40 repeat

1 reference

NB-ARC

1 reference

CARD domain

1 reference

WD40 repeat, conserved site

1 reference

Apoptotic Protease-Activating Factor 1, CARD domain

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016

1 reference

15 June 2016