(Q21117504)

http://www.ebi.ac.uk/interpro/protein/P51530

P-loop containing nucleoside triphosphate hydrolase

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P51530

DNA replication factor Dna2, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

4 iron, 4 sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

iron-sulfur cluster binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

5'-flap endonuclease activity

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Biochemical analysis of human Dna2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

5'-3' DNA helicase activity

1 reference

8 April 2019

Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

endonuclease activity

1 reference

8 April 2019

site-specific endodeoxyribonuclease activity, specific for altered base

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

single-stranded DNA helicase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Biochemical analysis of human Dna2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

5'-flap endonuclease activity

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Biochemical analysis of human Dna2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

gamma DNA polymerase complex

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

mitochondrial nucleoid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51530&geneProductId=UniProtKB:P51530

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

IBA

biological process

mitochondrial DNA repair

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

DNA double-strand break processing

1 reference

8 April 2019

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

DNA replication checkpoint signaling

1 reference

8 April 2019

Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

positive regulation of DNA replication

IMP

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

DNA replication, removal of RNA primer

1 reference

8 April 2019

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

G-quadruplex DNA unwinding

1 reference

8 April 2019

A balance between elongation and trimming regulates telomere stability in stem cells

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

1 reference

8 April 2019

A balance between elongation and trimming regulates telomere stability in stem cells

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

telomere maintenance via semi-conservative replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

replication fork reversal

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

regulation of signal transduction by p53 class mediator

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51530

http://purl.uniprot.org/uniprot/P51530

exact match

1 reference

stated in

Identifiers.org

has part(s)

DNA replication factor Dna2, N-terminal

1 reference

stated in

InterPro Release 71.0