Wikidata

(Q21987135)

English

KIT proto-oncogene receptor tyrosine kinase

mammalian protein found in Mus musculus

  • dominant spotting
  • spotted sterile male
  • tyrosine-protein kinase Kit
  • Steel Factor Receptor
  • proto-oncogene c-Kit
  • SCFR
  • Dominant white spotting
  • proto-oncogene tyrosine-protein kinase Kit
  • c-kit proto-oncogene protein
  • Kit
  • belly-spot
  • kit oncogene
  • mast/stem cell growth factor receptor Kit
In more languages

Statements

part of
molecular function
protein binding
determination method
IPI
9 references
retrieved
9 May 2019
stated in
The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Molecular cloning of the mouse APS as a member of the Lnk family adaptor proteins
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Complex interactions in EML cell stimulation by stem cell factor and IL-3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
retrieved
9 May 2019
stated in
Regulation of hematopoietic development in the aorta-gonad-mesonephros region mediated by Lnk adaptor protein
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IPI
cell component
external side of plasma membrane
determination method
IDA
IEA
ISO
15 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IEA
retrieved
9 May 2019
stated in
Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
GATA-3 is required for early T lineage progenitor development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
miR669a and miR669q prevent skeletal muscle differentiation in postnatal cardiac progenitors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Stat5 expression is critical for mast cell development and survival
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Stat5a is essential for the proliferation and survival of murine mast cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
retrieved
9 May 2019
stated in
Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05532
determination method
IDA
biological process

Identifiers

 
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