Wikidata

(Q21987363)

English

Serine/threonine-protein kinase PAK 1

mouse protein (annotated by UniProtKB/Swiss-Prot O88643)

  • CDC42/RAC effector kinase PAK-A
  • PAK-1
  • p65-PAK
  • Alpha-PAK
  • p21-activated kinase 1
In more languages

Statements

instance of
protein
0 references
molecular function
protein kinase activity
determination method
IDA
IEA
TAS
ISO
6 references
retrieved
14 February 2019
stated in
YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
TAS
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
ISO
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IEA
retrieved
14 February 2019
stated in
Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IDA
retrieved
14 February 2019
stated in
Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IDA
retrieved
14 February 2019
stated in
The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IDA
protein binding
determination method
IPI
6 references
retrieved
14 February 2019
stated in
Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1
GOA
curator
UniProt
UniProt protein ID
O88643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
retrieved
14 February 2019
stated in
Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42
GOA
curator
UniProt
UniProt protein ID
O88643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
retrieved
14 February 2019
stated in
Scrib regulates PAK activity during the cell migration process
GOA
curator
UniProt
UniProt protein ID
O88643
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
retrieved
14 February 2019
stated in
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
retrieved
14 February 2019
stated in
Bves directly interacts with GEFT, and controls cell shape and movement through regulation of Rac1/Cdc42 activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
retrieved
14 February 2019
stated in
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O88643
determination method
IPI
cell component
biological process

Identifiers

 
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