(Q2662393)

(1S,2S,4S,7Z,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

C15H20O3 (English)

20 September 2016

1 reference

2 references

(1R,2S,4S,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

2 references

(1R,2R,4S,7E,11R)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

2 references

(1aR,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one

1 reference

(1S,2R,4S,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

1 reference

1 reference

(1aS,4E,7aS,10aR,10bS)-1a,5-Dimethyl-8-methylene-1a,2,3,6,7,7aalpha,10aalpha,10bbeta-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(8H)-one

1 reference

1 reference

1 reference

(1S,2R,4R,7E,11R)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

1 reference

(1S,2S,4S,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one

1 reference

1 reference

C₁₅H₂₀O₃

1 reference

C15H20O3 (English)

20 September 2016

CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C

1 reference

C15H20O3 (English)

20 September 2016

C=C1C(=O)O[C@H]2[C@H]1CC/C(C)=C\CC[C@@]1(C)O[C@@H]21

0 references

found in taxon

Tanacetum parthenium

35 references

Comparison of Extraction Procedures for Parthenolide inTanacetum parthenium

Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kappaB.

Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium

3,4-β-Epoxy-8-deoxycumambrin B, A sesquiterpene lactone from Tanacetum parthenium

A bioassay for inhibition of serotonin release from bovine platelets

Airborne Compositae dermatitis: monoterpenes and no parthenolide are released from flowering Tanacetum parthenium (feverfew) plants

Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines

A proposal for the quality control of Tanacetum parthenium (feverfew) and its hydroalcoholic extract

A quantitative method for the estimation of parthenolide and other sesquiterpene lactones containing α-methylenebutyrolactone functions present in feverfew,Tanacetum parthenium

A simple method of isolating parthenolide from Tanacetum and other sensitizing plants

Chemical Mutagenesis and Parthenolide Biosynthesis in Feverfew (Tanacetum parthenium)

Comparative study of Tanacetum species growing in Bulgaria.

Determination of Parthenolide in Selected Feverfew Products by Liquid Chromatography

Effects of Drying Temperature and Storage on Parthenolide Concentration of Feverfew (Tanacetum parthenium L.) Leaves

Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro

Extraction and high-performance liquid chromatographic methods for the γ-lactones parthenolide (Chrysanthemum parthenium Bernh.), marrubiin (Marrubium vulgare L.) and artemisinin (Artemisia annua L.)

Feverfew and vascular smooth muscle: extracts from fresh and dried plants show opposing pharmacological profiles, dependent upon sesquiterpene lactone content

Feverfew extracts and parthenolide irreversibly inhibit vascular responses of the rabbit aorta

Feverfew (Tanacetum parthenium L.): tissue culture and parthenolide synthesis

Multi-Component Metabolic Classification of Commercial Feverfew Preparations via High-Field 1H-NMR Spectroscopy and Chemometrics

Occupational allergic contact dermatitis caused by decorative plants

Parthenolide content and bioactivity of feverfew (Tanacetum parthenium (L.) Schultz-Bip.). Estimation of commercial and authenticated feverfew products

Parthenolide Content of Feverfew (Tanacetum parthenium) Assessed by Hplc and1H-nmr Spectroscopy

Pharmacological activity of feverfew (Tanacetum parthenium (L.) Schultz-Bip.): assessment by inhibition of human polymorphonuclear leukocyte chemiluminescence in-vitro

Prostaglandin synthetase inhibitors in feverfew

Rapid extraction and high-performance liquid chromatographic determination of parthenolide in feverfew (Tanacetum parthenium)

Sesquiterpene lactones from feverfew, Tanacetum parthenium: isolation, structural revision, activity against human blood platelet function and implications for migraine therapy

The content of parthenolide and its yield per plant during the growth of Tanacetum parthenium

Enhancement of 1 alpha,25-dihydroxyvitamin D(3)-induced differentiation of human leukaemia HL-60 cells into monocytes by parthenolide via inhibition of NF-kappa B activity

Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.

Parthenolide induces apoptosis in glioblastomas without affecting NF-kappaB.

Parthenolide induces significant apoptosis and production of reactive oxygen species in high-risk pre-B leukemia cells

Parthenolide sensitizes ultraviolet (UV)-B-induced apoptosis via protein kinase C-dependent pathways.

Intra-specific variability of feverfew: correlations between parthenolide, morphological traits and seed origin

Allergic contact dermatitis caused by Artemisia and Chrysanthemum species. The role of sesquiterpene lactones

Tanacetum vulgare

5 references

Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro

Anti-inflammatory effects of South American Tanacetum vulgare

A simple method of isolating parthenolide from Tanacetum and other sensitizing plants

Effect of the chloroform extract of Tanacetum vulgare and one of its active principles, parthenolide, on experimental gastric ulcer in rats

Allergic contact dermatitis caused by Artemisia and Chrysanthemum species. The role of sesquiterpene lactones

Tanacetum niveum

1 reference

Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro

Anthemis cretica

1 reference

Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis

Anthemis macedonica

1 reference

Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis

Anthemis melampodina

1 reference

Sesquiterpene lactones as chemotaxonomic markers in genus Anthemis

Eriocephalus kingesii

1 reference

Sesquiterpene lactones and other constituents from Eriocephalus species

Magnolia virginiana

2 references

Sesquiterpenes from southern Magnolia virginiana

Sesquiterpenes from southern Magnolia virginiana

Staehelina fruticosa

2 references

Sesquiterpene lactones from Staehelina fruticosa.

Sesquiterpene lactones from Staehelina fruticosa.

Carpesium longifolium

1 reference

Xanthanolides, germacranolides, and other constituents from Carpesium longifolium

Cyathocline purpurea

1 reference

A germacranolide from Cyathocline lutea

Pentanema aschersonianum

1 reference

Sesquiterpenic lactones of Inula aschersoniana JANKA var. aschersoniana species

Magnolia denudata

1 reference

Cytocidal Principles of Magnolia Denudata

Magnolia grandiflora

3 references

A guaianolide from Magnolia grandiflora

Extraction of Bioactive Sesquiterpene Lactones from Magnolia grandiflora Using Supercritical Carbon Dioxide and Near-Critical Propane

Two new germacranolides from Magnolia grandiflora

Magnolia

1 reference

Lignans and sesquiterpenes from Magnolia praecocissima

Magnolia salicifolia

1 reference

Mosquitocidal Compounds from Magnolia Salicifolia

Magnolia champaca

2 references

Constituents of Michelia champaca and Lewis acid catalysed transformations of parthenolide into guaianolides

Sesquiterpene lactones from Michelia champaca

Magnolia nilagirica

1 reference

Sesquiterpene lactones from Michelia nilagirica root bark

Tanacetum argenteum

2 references

A guaianolide from Tanacetum argenteum subsp. flabellifolium

Sesquiterpenoids from Tanacetum argenteum subsp. canum var. canum

Tanacetum densum

1 reference

Sesquiterpene lactones from Tanacetum densum subsp. amani

Tanacetum larvatum

1 reference

Parthenolide from the aerial parts of Tanacetum larvatum

Tarchonanthus camphoratus

1 reference

Voltammetric determination of parthenolide in spiked human plasma and urine

Magnolia rajaniana

1 reference

Constituents of Michelia Rajaniana. Two new germacranolide amides

Magnolia baillonii

1 reference

Constituents of Paramichelia baillonii: a new antitumor germacranolide alkaloid

Magnolia ovata

1 reference

Constituents of the leaves of Magnolia ovata

Magnolia odora

1 reference

A new sesquiterpene lactone from Tsoongiodendron odorum Chun

Ambrosia dumosa

1 reference

Allergic contact dermatitis caused by Artemisia and Chrysanthemum species. The role of sesquiterpene lactones

Hirtellina fruticosa

1 reference

Sesquiterpene lactones from Staehelina fruticosa.

Asteraceae

1 reference

Effects of extracts ofTanacetum species on human polymorphonuclear leucocyte activityin vitro

subject has role

non-steroidal anti-inflammatory drug

1 reference

InChI=1S/C15H20O3/c1-9-5-4-8-15(3)13(18-15)12-11(7-6-9)10(2)14(16)17-12/h5,11-13H,2,4,6-8H2,1,3H3/b9-5-/t11-,12-,13-,15+/m0/s1

Medical Subject Headings

15 March 2018

Parthenolide

0 references

Identifiers

InChI

0 references

KTEXNACQROZXEV-PVLRGYAZSA-N

0 references

reason for deprecated rank

cannot be confirmed by other sources

1 reference

imported from Wikimedia project

ChEBI release 2020-09-01

CAS Registry Number

20554-84-1

1 reference

1 reference

English

(4Z)-1a,5-Dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one (English)

matched by identifier from

20 September 2016

PubChem CID

5420805

1 reference

Reaxys registry number

3550011

0 references

1 reference

English

CHEMBL3186408 (English)

20 September 2016

2 references

matched by identifier from

imported from Wikimedia project

1 reference

LY4220000

1 reference

English Wikipedia

DSSTox substance ID

DTXSID2040579

1 reference

matched by identifier from

DSSTOX compound identifier

DTXCID0020579

0 references

EC number

692-532-0

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.220.558

27 December 2018

ECHA Substance Infocard ID

(1S,2S,4R,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0²,⁴]tetradec-7-en-13-one (English)

quotation

CAS no.: 20554-84-1 (English)

100.220.558

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.220.558

27 December 2018

(1S,2S,4R,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.0²,⁴]tetradec-7-en-13-one (English)

quotation

CAS no.: 20554-84-1 (English)

1 reference

28 December 2019

PARTHENOLIDE (English)

quotation

CAS no.: 20554-84-1 (English)

MeSH descriptor ID

C002669

1 reference

Medical Subject Headings

14 March 2018

0 references

1 reference

6 July 2021

CAS no.: 20554-84-1 (English)

Immune Epitope Database and Analysis Resource

Parthenolide (English)

0 references

0 references

0 references

0 references

1 reference

4 February 2021

1 reference

6 April 2020

1 reference

28 October 2013

Microsoft Academic ID

2780321935

0 references

Nikkaji ID

J15.880A

1 reference

imported from Wikimedia project

Japanese Wikipedia

Wikimedia import URL

https://ja.wikipedia.org/w/index.php?title=パルテノリド&oldid=67244925

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C0894280

1 reference

inferred by common MeSH mappings on source and on Wikidata

UMLS 2023