(Q27651667)

English

Mechanistic and Structural Analysis of Aminoglycoside N -Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant † ‡

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scholarly article

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Mechanistic and Structural Analysis of Aminoglycoside N -Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant † ‡ (English)

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George A Jacoby

4

object named as

George A Jacoby

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John S Blanchard

6

object named as

John S Blanchard

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author name string

Matthew W Vetting

1

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Chi Hye Park

2

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Subray S Hegde

3

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David C Hooper

5

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language of work or name

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publication date

16 September 2008

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47

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37

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9825-35

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Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance

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Scaling and assessment of data quality

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The integration of macromolecular diffraction data

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Coot: model-building tools for molecular graphics

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Refinement of macromolecular structures by the maximum-likelihood method

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wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

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20 March 2017

Structure and functions of the GNAT superfamily of acetyltransferases

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Recent developments in the PHENIX software for automated crystallographic structure determination

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Mutagenesis analysis of a conserved region involved in acetyl coenzyme A binding in the aminoglycoside 6'-N-acetyltransferase type Ib encoded by plasmid pJHCMW1.

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29 September 2017

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29 September 2017

Molecular insights into aminoglycoside action and resistance

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Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States

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Versatility of aminoglycosides and prospects for their future

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Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection.

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Systematic analysis of a conserved region of the aminoglycoside 6'-N-acetyltransferase type Ib.

1 reference

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Aminoglycoside-modifying enzymes

1 reference

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Molecular cloning of amikacin resistance determinants from a Klebsiella pneumoniae plasmid

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Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6'-N-acetyltransferase Ib and IIa proteins

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Bacterial resistance to aminoglycoside antibiotics

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based on heuristic

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https://pubmed.ncbi.nlm.nih.gov/18710261

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based on heuristic

inferred from PubMed ID database lookup

A resin chromatographic analysis for kanamycin mixtures

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https://pubmed.ncbi.nlm.nih.gov/18710261

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based on heuristic

inferred from PubMed ID database lookup

Mechanisms of fluoroquinolone resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18710261

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI800664X

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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