Wikidata

(Q3141769)

English

Heat shock protein family B (small) member 1

mammalian protein found in Homo sapiens

  • estrogen-regulated 24 kDa protein
  • epididymis secretory protein Li 102
  • SRP27
  • stress-responsive protein 27
  • HSP 27
  • heat shock 27 kDa protein
  • 28 kDa heat shock protein
  • heat shock 27kD protein 1
  • heat shock protein beta-1
  • HSPB1
  • heat shock 27kDa protein 1
  • HSP27 Heat-Shock Proteins
In more languages

Statements

molecular function
protein binding
determination method
IPI
22 references
retrieved
17 October 2017
stated in
Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Inhibition of Daxx-mediated apoptosis by heat shock protein 27
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Proteomic and biochemical analysis of 14-3-3-binding proteins during C2-ceramide-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Dynamic protein-protein interaction wiring of the human spliceosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Identification of differential proteins in nasopharyngeal carcinoma cells with p53 silence by proteome analysis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Alteration of protein-protein interactions of congenital cataract crystallin mutants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
identical protein binding
determination method
IMP
IPI
6 references
retrieved
17 October 2017
stated in
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Dynamic protein-protein interaction wiring of the human spliceosome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Inhibition of Daxx-mediated apoptosis by heat shock protein 27
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IPI
retrieved
17 October 2017
stated in
Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IMP
retrieved
17 October 2017
stated in
Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IMP
cell component
cytoplasm
determination method
IEA
TAS
IDA
6 references
retrieved
17 October 2017
stated in
Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
TAS
retrieved
17 October 2017
stated in
Chaperone hsp27 inhibits translation during heat shock by binding eIF4G and facilitating dissociation of cap-initiation complexes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
TAS
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IEA
retrieved
17 October 2017
stated in
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IDA
retrieved
17 October 2017
stated in
HSPB7 is a SC35 speckle resident small heat shock protein
GOA
curator
UniProt
UniProt protein ID
P04792
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P04792&geneProductId=UniProtKB:P04792
determination method
IDA
biological process

Identifiers

MeSH descriptor ID
D055551
subject named as
HSP27 Heat-Shock Proteins
0 references
 
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